In developing countries, the risk of getting sick from eating food contaminated with Escherichia coli is very high. As a consequence multidrug resistance this bacterium, therapeutic alternative has been sought in plant kingdom. The Objective research was to evaluate antibacterial effect pot marigold (Calendula officinalis) essential oil (EO) on growth E. coli. Design/Methodology/Approach: activ...

We have studied the acute and subchronic oral toxicities of Calendula officinalis extract in male and female Wistar rats. A single acute C. officinalis extract dose of 2000 mg/kg dissolved in distilled water was administered by oral gavage for acute toxicity. Subchronic doses of 50, 250 and 1000 mg/kg/day were administered in drinking water. The major toxicological endpoints examined included a...