The main purpose of this study is developed and drug loaded nanoparticles of azelastine hydrochloride, an antiallergic drug and optimization in terms of chemical properties, drug concentration, polymer concentration, cross‐linking agent and stirring time. Nanoparticles of azelastine hydrochloride were fabricated using chitosan and sodium alginate as polymers by ionotropic pregelation method. Ca...

We consider the problem of inferring direct neural network connections from Calcium imaging time series. Inverse covariance estimation has proven to be a fast and accurate method for learning macroand micro-scale network connectivity in the brain and in a recent Kaggle Connectomics competition inverse covariance was the main component of several top ten solutions, including our own and the winn...

Using calcium oxide-based catalyst, optimization of two-stage trans-esterification processes at a fixed catalyst (1.0 wt. %) and molar ratio (1:6) was achieved. Processes were tested on Jatropha, Sweet Almond Sesame seed oils to produce compare biodiesel yields. An solution speed (629.630 rpm), temperature (26.661 oC), time (60 min) resulted in an 83.304% for refined jatropha (RJB) production, ...

For more than 20 years, reverse pharmacology has been the preeminent strategy to discover the activating ligands of orphan G protein-coupled receptors (GPCRs). The onset of a reverse pharmacology assay is the cloning and subsequent transfection of a GPCR of interest in a cellular expression system. The heterologous expressed receptor is then challenged with a compound library of candidate ligan...

In adult patients with ESRD, calcific uremic arteriolopathy (CUA) is an uncommon but life-threatening complication. No effective therapy exists, although anecdotal case reports highlight the use of sodium thiosulfate (STS), a calcium-chelating agent with antioxidant properties. CUA is rare in children, and STS use has not been reported. The objective of this study was to determine the influence...

Background: Biosurfactants are derived from microbes, plants, and animals. Acinetobacter junii B6 is a lipopeptide biosurfactant producer previously investigated for its structure, physicochemical, product aggregation properties. Objectives: In this study, we optimized the bioencapsulation of A. in calcium alginate hydrogel. Methods: was encapsulated using The formulation hydrogel full factoria...

This research focused on the evaluation of potential use a soil-isolated bacteria, identified as Staphylococcus equorum, for microbial-induced calcite precipitation (MICP) and copper removal. Isolated bacteria were characterized considering growth rate, urease activity, calcium carbonate precipitation, tolerance minimum inhibitory concentration (MIC) precipitation. Results compared with Sporosa...

Microbial-induced CaCO3 precipitation (MICP) is an innovative and rapidly developing technology for sand solidification. The idea this research project was built based on the concept of sustainable development environmental protection. specific material used solidification soluble calcium ions generated by reaction limestone waste, a kind calcium-rich industrial waste from quarry, acetic acid. ...