R. Abdel-Basset* Botany Department, Faculty of Science, Assiut University, Assiut, Egypt Z. Naturforsch. 53c, 33-38 (1998); received November ll/D ecem ber 8 , 1997 Calcium, Calcium Antagonists, Cell Wall Polysaccharides, Protoplasts, Vicia Faba The composition of newly synthesized cell walls starting from enzymatically isolated Zea mays mesophyll protoplasts was studied. The contents of pectin...

Wound healing is a natural response to restore the injured tissue to normal. Wound healing is also complicated process involving different cellular, molecular and biochemical mechanisms and various types of cytokines and growth factors. Calcium channel blockers belong to cardiovascular medicine and administrated to treatment of hypertension, angina and cardiac arrhythmia because of vasodilatory...

In lamprey spinal cord, intracellular calcium ([Ca2+]i) plays a key role in mechanisms regulating neuronal activity in the segmental network for locomotion. In this report, measurements of [Ca2+]i with fluo-3 in various regions of motoneurons in the intact spinal cord were obtained on a high speed confocal microscope following electrical stimulation. Likewise, rhythmic calcium fluctuations with...

BACKGROUND Having decided on a drug class, an individual drug needs to be chosen. OBJECTIVE This article discusses the same four factors used in deciding the generic drug within a class as well as between different drug classes: efficacy, safety, suitability, and cost. DISCUSSION The example of hypertension will be used to illustrate the choice of individual drugs within beta blockers and c...

objective: catsper is a voltage-sensitive calcium channel that is specifically expressed in the testis and it has a significant role in sperm performance. catsper (1-4) ion channel subunit genes, causes sperm cell hyperactivation and male fertility. in this study, we have explored targeting of the extracellular loop as an approach for the generation of antibodies with the potential ability to b...

Authors: Ferreira R. The use of diuretics (and beta-blockers) to treat hypertension has known a dramatic decline since the early 1980’s through to the early 1990s with the introduction of ACE-inhibitors and calcium channel blockers. However, thiazide diuretics are still a first line option to treat arterial hypertension, due to their efficacy and cost-effectiveness profile. We have presented ma...

Heterogeneity of response to antihypertensive therapy is a well-recognized clinical phenomenon. An agent that is antihypertensive in one patient may increase blood pressure in another or have no effect in a third. We believe that this variety of individual response to drug treatment can provide a new framework for the study of hypertensive subjects. Different patterns of response elicited by se...

The present study was focused on evaluation of locomotor cross-sensitization between nicotine and ethanol in mice. First, we demonstrated that, after 5 daily injections, nicotine (0.5 mg/kg, ip) produced sensitization to its own locomotor stimulant effect. Moreover, nicotine-experienced mice manifested an enhanced response to ethanol challenge (2 g/kg, ip) indicating the development of cross-se...

5-Hydroxytryptamine (5-HT) is a potent pulmonary vasoconstrictor and contributes to hypoxic pulmonary vasoconstriction and pulmonary arterial hypertension. Small intrapulmonary vessels are very sensitive to hypoxia and play a major role for blood flow regulation in the lung. Thus we have investigated the mechanisms involved in the calcium signal to 5-HT in rat small intrapulmonary artery (IPA)....