Calciphylaxis, also referred to as calcific uremic arteriolopathy, is a relatively rare but well described syndrome that occurs most commonly in patients with late stage CKD. It is characterized by very painful placques or subcutaneous nodules and violaceous, mottled skin lesions that may progress to nonhealing ulcers, tissue necrosis, and gangrene with a 1-year mortality rate >50%. The pathoge...

Calciphylaxis is a rare complication of chronic renal failure mostly with poor prognosis. Painful lesions on various skin surface areas are the most prominent feature of this serious disease. Subsequent infection of necrotic skin tissue is associated with the risk of sepsis. Pathophysiology is unclear, but several risk factors are known. The most important risk factor is impaired calcium-phosph...

Calciphylaxis is most commonly encountered in patients with end-stage renal disease; however, it is increasingly observed in nonuremic patients as well. It is important to consider and diagnose nonuremic calciphylaxis early, as prompt treatment and mitigation of associated risk factors is essential to improve long-term outcomes for these patients. Here, we present the case of a 71-year-old woma...

background: calciphylaxis is a serious disorder often observed in dialysis patients and less frequently in chronic renal failure patients with secondary hyperparathyroidism. mortality rate increases following the development of calciphylaxis, immediate application of parathyroidectomy along with other treatment options may be lifesaving. case presentation: a 44-year-old male patient had been on...

BACKGROUND Calciphylaxis is associated with a high mortality that approaches 80%. The diagnosis is usually made when obvious skin lesions (painful violaceous mottling of the skin) are present. However, visceral involvement is rare. We present a case of calciphylaxis leading to lower gastrointestinal (GI) bleeding and rectal ulceration of the GI mucosa. CASE REPORT A 66-year-old woman with past ...

Calciphylaxis is a rare, but potentially life-threatening condition usually observed in patients with end-stage chronic renal disease and characterized by small- and medium-sized blood vessel calcification leading to tissue ischemia. The clinical features are primarily cutaneous, consisting of skin necrosis and ulceration, mostly located in the lower extremities. We report a case of a 56-year-o...

Calcific uremic arteriolopathy (or calciphylaxis) is a severe complication of renal failure characterized by subcutaneous calcification of the small arteries and tissue necrosis. We describe the case of a woman receiving continuous cycling peritoneal dialysis with calciphylaxis involving upper and lower extremities. After intolerance of intravenous sodium thiosulfate and limited intravenous acc...

Tumoral calcinosis and calciphylaxis are uncommon complications of haemodialysis therapy and are associated with poor phosphate and calcium control. The use of calcium containing phosphate-binding agents in conjunction with high calcium dialysates may exacerbate these conditions by inducing a positive calcium balance. Despite their common aetiology, the two disorders are seldom reported to occu...

Abstract Background and Aims Risk factors with cutaneous calciphylaxis were analyzed in hemodialysis patients. Method Clinical data of patients who diagnosed admitted to Sichuan University West China Hospital hospitals Nephrology Union retrospectively collected. Noncalciphylaxis center randomly selected as the controls. Group 1: The 1:1 matched cases controls by age (year, within ±3) duration (...

A case of severe calciphylaxis in a patient with End Stage Renal Disease on peritoneal dialysis is presented. Diagnosis was based on medical history and clinical findings and was confirmed by skin biopsy. A multidisciplinary medical team was involved in the patient’s management who was treated with intravenous sodium thiosulfate, intensified hemodialysis sessions, parathyroidectomy and surgical...