Abstract Introduction Calcinosis cutis is a common complication of pediatric rheumatologic diseases. However, there currently no consensus on first-line treatment. Bisphosphonates have been described as successful treatment in several case studies, but most these cases are limited to patients with isolated juvenile dermatomyositis or systemic sclerosis. Specifically, reports their usefulness tr...

A case of Raynaud's phenomenon, was complicated with autoimmune hepatitis (AIH) during the clinical course, and subsequently with gangrene of the fingertips caused by CRST syndrome (calcinosis cutis, Raynaud's phenomenon, sclerodactyly and telangiectasia). The presence of anticentromere antibodies is rare in AIH; to date, there has been only one report of a combination of AIH and CRST syndrome....