background: the development of resistance to antimicrobial agents is a major problem in chemotherapy. finding agents which potentiate antimicrobial activity could be favorable. there are some reports that methylxanthines changed the inhibitory effect of antibacterial agents. thus, possible synergistic effect of methylxanthines, aminophylline and caffeine on some antibiotics, carbenicillin, ceft...

Caffeine is the most widely used psychoactive substance in the world. Although adolescents are the most rapidly increasing group of caffeine consumers, few studies have been done on the effects of caffeine on the still-developing adolescent brain. Since caffeine has been associated with stress reactivity and anxiety behavior, this study examined the effect of adolescent caffeine consumption on ...

the aim of the present study was to investigate the effect of two programs of standard sets and circuit weight training with different intensities on response of excess post exercise oxygen consumption (epoc) in young men. for this purpose, twelve healthy men (mean±sd: age, 21.92±1.1 years; height, 175.17±4.55cm; weight, 69.74±7.5kg) were voluntarily selected and participated in two stages of t...

Background There is evidence for a positive relationship between cigarette and coffee consumption in smokers. Cigarette smoke increases metabolism of caffeine, so this may represent a causal effect of smoking on caffeine intake. Methods We performed Mendelian randomization analyses in the UK Biobank (N = 114 029), the Norwegian HUNT study (N = 56 664) and the Copenhagen General Population Stu...

Caffeine undergoes 3-N-demethylation via CYP1A2, as well as 1-N-demethylation, 7-N-demethylation and 8-hydroxylation, which may involve other CYP isoenzymes. The aim of the present study was to investigate the influence of clomipramine, desipramine, sertraline, nefazodone and mirtazapine on cytochrome P-450 activity measured by caffeine oxidation in rat liver microsomes. The obtained results sh...

Literature examining the effects of aerobic exercise training on excess postexercise oxygen consumption (EPOC) is sparse. In this study, 9 male participants (19-32 yr) trained (EX) for 12 wk, and 10 in a control group (CON) maintained normal activity. VO(2max), rectal temperature (T(re)), epinephrine, norepinephrine, free fatty acids (FFA), insulin, glucose, blood lactate (BLA), and EPOC were m...

Black tea consumption has been shown to improve peripheral vascular function. Its effect on brain vasculature is unknown, though tea contains small amounts of caffeine, a psychoactive substance known to influence cerebral blood flow (CBF). We investigated the effects on CBF due to the intake of tea components in 20 healthy men in a double-blinded, randomized, placebo-controlled study. On separa...

background and aim: caffeine at low doses blocks adenosine receptors. these receptors are present in all parts of the body including auditory and vestibular system. this study aimed to evaluate the effects of caffeine on cervical vestibular evoked myogenic potential (cvemp). methods: in this interventional double-blind study, 40 cases (20 females and 20 males) aged 18-25 years were randomly ass...