نتایج جستجو برای: cacs

تعداد نتایج: 416  

2018
Masashi Fujita Nagahide Matsubara Ikuo Matsuda Kazuhiro Maejima Ayako Oosawa Tomoki Yamano Akihiro Fujimoto Mayuko Furuta Kaoru Nakano Aya Oku-Sasaki Hiroko Tanaka Yuichi Shiraishi Raúl Nicolás Mateos Kenta Nakai Satoru Miyano Naohiro Tomita Seiichi Hirota Hiroki Ikeuchi Hidewaki Nakagawa

Inflammatory bowel disease (IBD) increases the risk of colorectal cancer, known as colitis-associated cancer (CAC). It is still unclear what driver mutations are caused by chronic inflammation and lead to CAC development. To get insight into this issue, we investigated somatic alterations in CAC. We performed exome sequencing of 22 fresh CACs and targeted sequencing of 43 genes on 90 archive sp...

Journal: :Journal of Nuclear Cardiology 2021

2015
Natalia G. Rocha Allan R. K. Sales Leticia A. Penedo Felipe S. Pereira Mayra S. Silva Renan L. Miranda Jemima F. R. Silva Bruno M. Silva Aline A. Santos Antonio C. L. Nobrega

Increased levels of adhesion molecules or metalloproteinases (MMPs) may indicate endothelial dysfunction. Exercise mobilizes circulating angiogenic cells (CACs) from bone marrow in healthy subjects, improving vascular function. However, it is unclear whether this mechanism is preserved in the early stages of metabolic syndrome (early MetS). We aimed to evaluate the acute effects of exercise on ...

Journal: :Circulation 2000
Z X He T D Hedrick C M Pratt M S Verani V Aquino R Roberts J J Mahmarian

BACKGROUND Detection of subclinical coronary artery disease (CAD) before the development of life-threatening cardiac complications has great potential clinical relevance. Electron beam computed tomography (EBCT) is currently the only noninvasive test that can detect CAD in all stages of its development and thus has the potential to be an excellent screening technique for identifying asymptomati...

2015
Fabiola Olivieri Liana Spazzafumo Massimiliano Bonafè Rina Recchioni Francesco Prattichizzo Fiorella Marcheselli Luigina Micolucci Emanuela Mensà Angelica Giuliani Gabriele Santini Mirko Gobbi Raffaella Lazzarini Massimo Boemi Roberto Testa Roberto Antonicelli Antonio Domenico Procopio Anna Rita Bonfigli

Innovative biomarkers are required to manage type 2 diabetic patients (T2DM). We focused our study on miR-126-3p and miR-21-5p levels, as biomarkers of endothelial function and inflammation. MiRNAs levels were measured in plasma from 107 healthy subjects (CTR) and 193 diabetic patients (T2DM), 76 without (T2DM NC) and 117 with (T2DM C) complications. When diabetic complication were analysed as ...

Journal: :European Journal of Echocardiography 2023

Abstract Funding Acknowledgements Type of funding sources: None. Introduction Current guidelines recommend not to routinely test patients with chest pain and low pretest probability (PTP <15%) obstructive coronary artery disease (CAD) but envisage the use risk modifiers such as calcium score (CACS) refine patient selection for testing. The aim this study was assess cost-effectiveness (CE...

Journal: :Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2007
Andrzej Kraśniak Maciej Drozdz Mieczysław Pasowicz Grzegorz Chmiel Martyna Michałek Dorota Szumilak Piotr Podolec Piotr Klimeczek Małgorzata Konieczyńska Ewa Wicher-Muniak Wiesława Tracz Thao N'guyen Khoa Jean-Claude Souberbielle Tilman B Drueke Władysław Sulowicz

BACKGROUND Atherosclerosis and vascular calcifications are common causes of morbidity and mortality in maintenance haemodialysis patients. In addition to the well-known traditional risk factors, uraemia-specific factors appear to enhance dramatically the progression of the pathological processes involved. The aim of the present study was to evaluate the degree of atherosclerosis and vascular ca...

Journal: :The Journal of infectious diseases 2015
Caroline Schmidt-Lucke Thomas Zobel Sonja Schrepfer Uwe Kuhl Dong Wang Karin Klingel Peter Moritz Becher Henry Fechner Tanja Pozzuto Sophie Van Linthout Dirk Lassner Frank Spillmann Felicitas Escher Sebastian Holinski Hans-Dieter Volk Heinz-Peter Schultheiss Carsten Tschope

Human parvovirus B19 (B19V) is a common pathogen in microvascular disease and cardiomyopathy, owing to infection of endothelial cells. B19V replication, however, is almost restricted to erythroid progenitor cells (ErPCs). Endothelial regeneration attributable to bone marrow-derived circulating angiogenic cells (CACs) is a prerequisite for organ function. Because of many similarities of ErPCs an...

Journal: :European journal of dentistry 2007
Yildiray Sisman Elif Tarim Ertas Cumali Gokce Ahmed Menku Mustafa Ulker Faruk Akgunlu

OBJECTIVES The aim of this study is to determine retrospectively the presence of carotid artery calcifications (CACs) detected on panoramic radiographs (PRs) in a group of Turkish population. Further, the relationships between CACs and gender, life style, and medical history were evaluated. METHODS During the years 2004 to 2006, a random sample of 1282 PRs was collected from patients older th...

2018
Gabriel Lichtenstein Amichai Perlman Shoshana Shpitzen Ronen Durst Dorit Shaham Eran Leitersdorf Auryan Szalat

BACKGROUND Previous studies have established a correlation between coronary artery calcification (CAC) measured by ECG-gated chest computed tomography (CT) and cardiovascular disease. Recent reports which included asymptomatic patients suggest that CAC measured on non-ECG gated CT is similarly associated with cardiovascular risk. This study investigates the correlation between the Framingham Ri...

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