•The specificity of a glutaminase subunit for synthase has been inverted•The switch was achieved by both computational and data-driven approach•The designed complexes were stable catalytically active The formation specific protein in cell is non-trivial problem given the co-existence thousands different polypeptide chains. A particularly difficult case are two glutamine amidotransferase (anthra...

There is a national trend for swine enterprises to increase in size due to cost efficiencies associated with economies of scale. This study was performed to evaluate the effect of farm size on manure application management for a survey o f 391 swine producers in Minnesota. There was a statistically significant effect of farm size on almost all of the variables evaluated. As farm size increased:...