Here, we studied the underlying mechanism of aldosterone (Aldo)-induced vascular endothelial cell damages by focusing on ceramide. We confirmed that Aldo (at nmol/L) inhibited human umbilical vein endothelial cells (HUVEC) survival, and induced considerable cell apoptosis. We propose that ceramide (mainly C18) production might be responsible for Aldo-mediated damages in HUVECs. Sphingosine-1-ph...

The aim of this study was to provide information on the fatty acid profile of different adipose depots – subcutaneous (upper and inner backfat layers) and intramuscular (m. Longissimus dorsi) in East Balkan pigs. The animals were reared in free-range conditions and slaughtered at an average live weight of 107±1.65kg. The results of the study showed that the various adipose tissues in pigs have ...

Rat brain increases in weight after birth in three stages: (I) rapidly for the first 2 weeks, (II) at a lower rate from 2 to 5 weeks, and (III) at a still lower rate from 5 weeks to 5 months. During the succeeding period, designated IV, it maintains constant weight up to 1 year of age. Brain ganglioside content increased linearly during I and II, more slowly during III, and diminished during IV...

Vitamin D (VD) is a fat-soluble vitamin with high deficiency levels evident globally. Bioaccessibility of VD influenced by formation mixed micelles (MM) during digestion. This study assessed the impact fatty acid (FA) type, phospholipid concentration on MM and stability to salts. occurred at NaCl KCl concentrations ranging from 20 100 mM, when octanoic (C8) or stearic (C18) were used. hydrodyna...

Background. Desaturase enzymes are involved in the formation of monoenoic acids from saturated fatty acids. One such enzyme is stearyl-CoA-desaturase (SCD1), which converts stearic acid to oleic acid. The aim this work was determine effect edible fats with different compositions on SCD1 activity.
 Methods. High linoleic sunflower oil (HLSO), high (HOSO) and palm (PO) were used. rats fed fo...