Curcuma, a genus of rhizomatous herbaceous species, has been used as a spice, traditional medicine, and natural dye. In this study, the metabolite profile of Curcuma extracts was determined using gas chromatography-time of flight mass spectrometry (GC/TOF MS) and ultrahigh-performance liquid chromatography-quadrupole time-of-flight mass spectrometry (UPLC/Q-TOF MS) to characterize differences b...

Atherothrombotic diseases such as myocardial or cerebral infarction are serious consequences of the thrombus formed xin blood vessels. Thrombolytic agents are used to dissolve the already formed clots in the blood vessels; however, these drugs have certain limitations which cause serious and sometimes fatal consequences. Herbal preparations have been used since ancient times for the treatment o...

Non-enzymatic glycation and the accumulation of advanced glycation end products (AGEs) are associated with various diseases states, including complications of diabetes and aging. Hydroalcoholic extracts of several kinds of spices (16) and chilies (21) of culinary used in traditional Mexican cuisine were tested for in vitro inhibition of non-enzymatic glycation of bovine serum albumin. Of these,...

We explored, using nuclear magnetic resonance (NMR) metabolomics and fatty acids profiling, the effects of a common nutritional complement, Curcuma longa, at a nutritionally relevant dose with human use, administered in conjunction with an unbalanced diet. Indeed, traditional food supplements have been long used to counter metabolic impairments induced by unbalanced diets. Here, rats were fed e...

Knee effusion is an abnormal accumulation of the fluid in the knee capsule or the adjoining supra-patellar bursa secondary to the irritation/inflammation in the joint synovium. It is seen in approximately 8-10 % of the total patients suffering from osteo-arthrosis. Kroṣṭukaśīrṣaas described in Ayurveda, can be corelated with knee effusion. In Present clinical trial an effort has been made to ev...

ment and spice, has been used therapeutically in traditional folk medicine for a wide range of ailments, including wound healing, urinary tract infection, and liver ailments. Although evidence suggests that a C. longa extract also has considerable gastroprotective and antiulcerogenic effects, its mechanism of action remains unclear. The genes encoding four histamine receptor subtypes (H1, H2, H...

The objectives of this study were to explore the inhibition mechanism of lung cancer cells A549 and H460 by curcuminoid extracts and nanoemulsions prepared from Curcuma longa Linnaeus. In addition, human bronchus epithelial cell line BEAS-2B (normal cell) was selected for comparison. A high-performance liquid chromatography (HPLC) method was developed to separate and quantify the various curcum...

Aim: The present investigation has been conducted to evaluate the hepatoprotective effect of Curcuma longa against lead induced toxicity. Materials and Methods: For this study, 24 Wistar albino rats were taken. Control group (n=8), group – I rats (n=8) were given lead acetate @ 1000 mg/kg bodyweight (BW) and group – II rats (n=8) were treated with Curcuma longa @ 500 mg/kg BW along with lead ac...

Increasing numbers of Double-crested Cormorants (Phalacrocorax auritus) in the Mississippi River Delta, USA, have been observed over the past few decades. This piscivorous bird is a definitive host for numerous digenetic trematodes, some of which may cause pathology in a fish host. We conducted a 2-yr survey of intestinal trematodes in 35 Double-crested Cormorants collected in the Mississippi D...