Kefir is a dairy-based probiotic beverage with high antioxidant activity, among other health benefits. To extend kefir’s beneficial effects to non-dairy consumers, studies on kefir fermentation using alternative matrices (referred as water kefir) are needed. As such, the purpose of this study was formulate novel Russian olive, product activity and potential properties. end, olive (RWK) process ...

Objectives: To review the literature on the toxicity of Callilepis laureola, and to assess the cytotoxicity of C. laureola in human hepatoblastoma Hep G2 cells in vitro. Design and methods: Cells were incubated for up to 48 h in the presence of increasing concentrations of an aqueous extract of C. laureola (0.3–13.3 mg/mL). Cytotoxicity was quantitated spectrophotometrically by the metabolism o...

Cissus quadrangularis L. is a promising remedy prescribed in the ancient Ayurvedic literature for bone fracture healing properties. As this activity has been extensively investigated and well established, a range of formulations containing C. quadrangularis has been marketed. This work reports the development and validation of a reliable RP-HPLC method for the analysis of phytosterols in the va...

BACKGROUND Lanthanum carbonate and sevelamer carbonate are non-calcium-based phosphate binders used to manage hyperphosphataemia in patients with chronic kidney disease (CKD). Patients with CKD may require intravenous or oral active vitamin D. We investigated the effects of lanthanum carbonate and sevelamer carbonate on the bioavailability of oral calcitriol. METHODS This was a three-period, ...

Connexin43 mimetic peptide (Cx43MP) has been intensively investigated for its therapeutic effect in the management of inflammatory eye conditions, spinal cord injury, wound healing and ischemia-induced brain damage. Here, we report on a validated stability-indicating reversed-phase high performance liquid chromatography (RP-HPLC) method for the quantification of Cx43MP under stress conditions. ...

This study was carried out to investigate in vitro fertilization and development of in vitro matured pig oocytes inseminated with the Duroc boar sperm by different sperm washing media after thawing of the 5 ml frozen straws. Immature follicular oocytes (30-40) were transferred into each well of a Nunc 4-well multidish containing 500 μl mTCM199 maturation medium. The sperm rich portion of ejacul...

Objective(s):[p1]  This study highlights xylanase overproduction from Bacillus mojavensis via UV mutagenesis and optimization of the production process. Materials and Methods:Bacillus mojavenis PTCC 1723 underwent UV radiation. Mutants’ primary screening was based on the enhanced Hollow Zone Diameter/ Colony Diameter Ration (H/C ratios) of the colonies in comparison with the wild strain on Xyla...

Adverse reactions to iron dextran are usually delayed and consist of joint pain, vomiting, nausea, headache, and fever. Lifethreatening reactions to iron dextran have been reported [1,2]. We report the case of a 48-year-old woman who experienced a severe reaction to iron dextran and who was able to receive the drug after undergoing a series of tolerance induction protocols. The patient had celi...

Type IV collagen, a nonfibrillar type, is ubiquitously expressed in the basement membrane around cardiomyocytes. Canstatin, a cleaved product of α2 chain of type IV collagen, is an antiangiogenic factor. Because it has not been clarified whether canstatin exerts other biological activities in heart, we investigated the effects of canstatin on adult rat cardiac fibroblasts. Cell migration was de...

background : the aim of the present study was to evaluate the effects of metronidazole and albendazole against clinical isolates of giardia lamblia in vitro. methods : from all human samples of containing cysts, 10 isolates were successfully excysted in vitro . trophozites viability was assessed by eosine 0.1% and cultured axenically in tyi-s-33 modified medium supplemented with heat inactivate...