Combined therapy with clarithromycin (CLTR) and N–acetyl cysteine (NAC) may be useful in diseases with impaired oxidant-antioxidant balance, fibroblast proliferation, and collagen deposition such as pulmonary fibrosis. Activated inflammatory cells which accumulate in the lower airways may release increased amounts of reactive oxygen species (ROS) when accompanied with a deficiency in glut...

conclusions it seems that testosterone in low dose, i.e. physiologic dose, protects kidneys against cp-induced nephrotoxicity; however, special care is needed in cp therapy of patients with high levels of ts. results cp increased the serum levels of blood urea nitrogen (bun), creatinine (cr), and malondialdehyde (smda) as well as kidney weight (kw), bodyweight (bw) loss, and kidney tissue damag...

Objective: The objective of this study is to compare the effectivity of captopril, losartan, and amlodipine on hypertension in rat model of gentamicin-induced renal failure. Methods: Adult male Wistar rats weighing 175-225 g are used. The rats were divided into 5 groups: negative control, positive control, captopril 120 mg/kg bw, losartan 20 mg/kg bw, and amlodipine 10 mg/kg bw group. All group...

protein amyloid beta (a?), as the pathologic hallmark of alzheimer disease (ad), increases in the brain of diabetic patients. the aim of this study was to investigate the effect of 6 weeks of voluntary wheel running combined with allium paradoxum extract on cortex amyloid beta (a?1-42) levels in diabetic rats induced with alloxan. for this purpose, 42 male wistar rats (weight 185+1 gr, 8 weeks ...

Different plants are traditionally applied in the treatment of different diseases, including chest pains, hypertension, and inflammation, among others. This study scientifically evaluated curative effects X. americana P. capensis leaf aqueous extracts rats induced with myocardial infarction. The were randomly distributed as follows: Normal control group, consisting treated oral normal saline; N...