Previous numerical and analytical work has shown that synaptic coupling can allow a network of model neurons to synchronize despite heterogeneity in intrinsic parameter values. In particular, synchronous bursting oscillations can arise in a network with excitatory synaptic coupling, even in the absence of intrinsically bursting neurons. In this work, we explore how the intrinsic dynamics of neu...

Rhythmically active networks are typically composed of neurons that can be classified as silent, tonic spiking, or rhythmic bursting based on their intrinsic activity patterns. Within these networks, neurons are thought to discharge in distinct phase relationships with their overall network output, and it has been hypothesized that bursting pacemaker neurons may lead and potentially trigger cyc...

The generation of bursting spike activity in the deeper layers of the superior colliculus (SC) is a critical determinant of decision making in the initiation of orienting behaviors, such as saccades. The bursting activity exhibits a typical threshold effect that may arise from a nonlinear signal amplification process in the deeper layers of the SC. We used whole-cell patch-clamp recordings in r...

Thalamic neurons have an exclusive property named bursting response. Bursting response seems to have a critical role in producing saliency map and encoding conspicuity of locations during visual attention. Attention window is developed in thalamus due to its retinotopic organization. The global competitive network in thalamic reticular nucleus (NRT) determines which thalamic cells should produc...

In the present study we have examined effects of ethanol and magnesium on Ni(2+)-induced bursting of leech Retzius cells. Saline with 3 mmol/l NiCl2 induced spontaneous bursting activity, characterized by rapid depolarizations to a plateau level during which bursts of action potentials occurred. To test for the mechanism of bursting initiation external Na+ was completely removed. Removal of ext...

The output of a dynamical system in a regime of homoclinic chaos transforms from a continuous train of irregularly spaced spikes to clusters of regularly spaced spikes with quiescent periods in between (bursting), provided a low frequency portion of the output is fed back. We provide experimental evidence of such an autonomous bursting by a CO2 laser with feedback. The phenomena here presented ...

Phasic respiratory bursting in the facial nerve (FN) can be uncoupled from phrenic bursting by application of 9 cmH(2)O positive end-expired pressure (PEEP). This response reflects excitation of expiratory-inspiratory (EI) and preinspiratory (Pre-I) facial neurons during the Pre-I period and inhibition of EI neurons during inspiration (I). Because activation of pulmonary C-fiber (PCF) receptors...

Contents 1. Introduction 5 1.1. Nonlinear behaviors, time scales, our approach 5 1.2. Electrical activity of cells 6 2. Revisiting the Hodgkin-Huxley equations 10 2.1. Background and formulation 10 2.2. Hodgkin-Huxley gating equations as idealized kinetic models 12 2.3. Dissection of the action potential 13 2.3.1. Current-voltage relations 13 2.3.2. Qualitative view of fast-slow dissection 15 2...

The growing pollen tube is central to plant reproduction and is a long-standing model for cellular tip growth in biology. Rapid osmotically driven growth is maintained under variable conditions, which requires osmosensing and regulation. This study explores the mechanism of water entry and the potential role of osmosensory regulation in maintaining pollen growth. The osmotic permeability of the...