To assess the outcome of burn patients with neuropsychiatric disorders, we performed a 7-year retrospective review of burn patients admitted to the National Defense Medical College. Seventy-seven skin burn patients over 10 years of age were included in this study and divided into two groups, neuropsychiatry and control groups. The neuropsychiatry group consisted of self-inflicted burn patients ...

Background: General practitioners are the first who visit burn patients and they first calculate burn size and required fluid for the patient. Error in calculation can be disastrous. The purpose of this study is to compare four methods of estimating burn size to teach students. Methods: This is a descriptive-analytic study on 37 medical students. Four methods of estimating burn percentage was t...

Definitions It is very important for the clinician caring for a burn victim to know the depth, or degree, of burn. A first-degree burn is superficial, dry, painful to touch, and heals in less than 1 week. A second-degree burn is partial thickness and pink or possibly mottled red. It exhibits bullae or frank weeping on the surface. It usually is painful unless classified as deep and heals in 1 t...

BACKGROUND Gram negative infection is a major determinant of morbidity and survival. Traditional teaching suggests that burn wound infections in different centres are caused by differing sets of causative organisms. This study established whether Gram-negative burn wound isolates associated to clinical wound infection differ between burn centres. METHODS Studies investigating adult hospitalis...

This study examined the effects of major burn injury on the cellular distribution of several PKC isoforms in adult rat hearts and examined the hypothesis that PKC plays a regulatory role in cardiomyocyte cytokine secretion. Burn trauma was given over 40% total body surface area in Sprague-Dawley rats. An in vitro model of burn injury included addition of burn serum, 10% by volume, to primary ca...

The causative organisms of burn wound infection are aerobic and anaerobic bacteria, fungi, and yeasts [1,2]. Viral burn wound infection is rarely reported but does occur. Herpes virus family, including herpes simplex virus and varicella zoster virus, are the most frequent causative agents [3]. However, bacteria are the predominant isolates of burn wound infection. Aspergillus species are the mo...

OBJECTIVE To validate the use of photographic burn wound assessment in evaluation of burn size and wound characteristics. METHODS Feasibility study of agreement between methods of measurement of burn size and characteristics, in patients admitted to the burn unit at Kamuzu Central Hospital (KCH), Malawi, over two months in 2011. Burn wounds were photographed and assessed clinically, concurren...

HYPOTHESIS The use of albumin in the early resuscitation formula after major burn has been forbidden because of its damaging effect on the gut barrier function. We hypothesize that inhibition of the inducible isoform of nitric oxide synthase to stabilize endothelial permeability and to retain albumin in the vascular space will ameliorate the major trauma-induced gut barrier dysfunction. DESIG...

Advances in burn care have a long history with accelerated development within the last 50 years. The principal areas of burn treatment include dressings, antimicrobials, fluid resuscitation, burn wound excision, grafting of skin, and skin substitution. This review presents a historical outline of these areas, their current status, and prospects for the future of burn care.

Severe burn injury evokes hypermetabolism and muscle wasting, despite nominally adequate nutrition. Although there is much information on whole organism and isolated tissue metabolism after burn injury, data examining regional burn hypermetabolism in vivo are lacking. Using surgically implanted (general anesthesia) regional vascular catheters and primed constant infusion of l-[1-(13)C]phenylala...