the authors describe a case of histiocyte-rich b-cell lymphoma (hr-bcl), a variant of diffuse large b-cell lymphoma, in a 51-year-old man. the patient presented with large axillary lymphadenopathy. histopathologic and immunohistochemical examination of lymph node biopsy revealed diffuse effacement of the lymph node architecture by reactive histiocytes and neoplastic cd20 positive b cells. react...

background : there are only a few reports that exist regarding primary non-hodgkin lymphoma of the genital tract. in this article, one case of primary b-cell type non-hodgkin lymphoma (nhl) of the cervix is presented. case history: a 45 year-old woman presented bloody vaginal  discharge. upon vaginal examination, the cervix was found to be enlarged. cervical biopsy revealed b-cell type non-hodg...

primary breast lymphoma represents less than 1% of all primary breast malignancies and most primary breast lymphomas are of b-cell origin. the association of anaplastic lymphoma kinase (alk) negative anaplastic large cell lymphoma (alcl), a very rare form of primary breast lymphoma, with silicone-filled breast implants has been suggested and several case reports supported this proposal, especia...

Diffuse large B-cell lymphoma is the most common type of non-Hodgkin lymphoma. MicroRNAs (miRNAs) are endogenous small RNA, which can regulate gene expression at the post-transcriptional level. MiRNA profiling has shown a great potential as novel diagnostic and prognostic biomarkers. The present study was performed at the Nemazee Teaching Hospital (Shiraz, Iran) from 2011 to 2013.The aim of thi...

background epstein-barr virus (ebv) is a dna virus which belongs to the herpesviridae family and in γ-herpesvirus subfamily, has been infected about 95% of the world’s population. ebv is transmitted through saliva and associated with different disease such as infectious mononucleosis, nasopharyngeal carcinoma, burkitt`s lymphoma, hodgkin and non-hodgkin`s lymphoma. the study proposed to determi...

Immunoproliferative small intestinal disease (IPSID) is the syndrome associated with Mediterranean lymphoma (a rare form of non-Hodgkin’s lymphoma). Many of the patients diagnosed with secretory IPSID have variable level of abnormal immunoglobulins in serum or other bodily fluids, identified as truncated alpha heavy chain globulins. Most cases are characterized by a loss of ability to synthesiz...

purpose: to report a patient with an intraocular lymphoma with history of treated brain lymphoma. case report: a 45-year-old female was referred with moderate chronic intermediate uveitis of both eyes that was unresponsive to medications. she had history of treated brain lymphoma with chemotherapy and radiotherapy 6 years before presentation. systemic workup, laboratory evaluation, brain and or...

Abstract Background Involvement of lacrimal apparatus by Non Hodgkin lymphoma as a first manifestation is extremely rare and only three cases have been reported in children. The purpose of this report is to determine the clinical characteristic of patient with primary involvement of lacrimal apparatus with lymphoma. Case presentation A 7-year-old girl with history of tearing, gradually prog...

abstract we report a 30 year old woman who presented with a painless preauricular mass of two months duration. superficial parotidectomy was performed for the patient. histological examination and immunohistochemical findings were in favor of mixed cellularity hodgkin’s lymphoma (mchd). according to this diagnosis the patient received local radiotherapy and during 4 months of follow-up no recur...