an abnormally small oral orifice is defined as microstomia. microstomia may result from epidermolysis bullosa (eb), which consists of a group of disorders characterized by the presence of mechanical fragility of the skin with recurrent development of blisters and vesicles, resulting from minor mechanical friction or trauma. since such patients have a small oral aperture, it may be impossible to...

background and aim kindler syndrome is a subtype of epidermolysis bullosa with gingival fragility and periodontitis as common oral manifestations of these patients. because of the early onset and rapid progression of periodontitis in these patients, clinical management of their oral status is an important aspect of their multidisciplinary care and treatment case presentation we present a succes...

La epidermólisis bullosa es una enfermedad genética. Se manifiesta por la aparición de ampollas, úlceras posteriores a roces o traumatismos. Las lesiones pueden tener localización cutánea y extra cutánea. Para realizar el diagnostico se debe presente los antecedentes heredofamiliares, clínica, microscopia exámenes laboratorio. Presentamos un caso Epidermólisis Bullosa diagnosticado en recién na...

INTRODUCTION Cholesteatoma is a relatively common disease within the middle ear cavity, but rarely it manifests in the paranasal sinuses. There is, to the best of our knowledge, only one other published case of cholesteatoma inside the concha bullosa in the English language literature. CASE PRESENTATION An 81-year-old Caucasian woman was admitted to our hospital complaining of nasal obstructi...

Epidermolysis bullosa dystrophica is a rare hereditary disorder which presents significant anaesthetic problems. These include malnutrition and anaemia; electrolyte imbalance in severe cases; renal failure and amyloidosis in progressive disease; association with porphyria; a history of steroid therapy. Technical problems associated with the necessity to avoid trauma to the skin and mucous membr...

A knot polymer, poly[bis(2-acryloyl)oxyethyl disulphide-co-2-(dimethylamino) ethyl methacrylate] (DSP), was synthesized, optimized and evaluated as a non-viral vector for gene transfection for skin cells, keratinocytes. With recessive dystrophic epidermolysis bullosa keratinocytes (RDEBK-TA4), the DSP exhibited high transfection efficacy with both Gaussia luciferase marker DNA and the full leng...

conclusions among anatomic variations, septal deviation and concha bullosa are predisposing factors for chronic sinusitis and we recommend that patients with chronic sinusitis be treated by surgical procedures. background identifying predisposing factors for chronic sinusitis is very important. objectives anatomical variation of the lateral nasal wall has been investigated in several studies an...