An efficient one-pot process for the synthesis of 3-substituted phospholanes and α,ω-bisphospholanes was developed. The method involves the replacement of aluminium in aluminacyclopentanes, prepared in situ by catalytic cycloalumination of α-olefins and α,ω-diolefins, by phosphorus atoms on treatment with dichlorophosphines (R'PCl2). Hydrogen peroxide oxidation and treatment with S8 of the synt...

The vinylideneruthenium(II) complexes bearing bulky and basic tertiary phosphine ligands, RuCl2(=C=CHPh)L2 (L = PPri3, PCy3), serve as good catalyst precursors for (Z)-selective cross-dimerization between arylacetylenes and silylacetylenes in the presence of N-methylpyrrolidine.

Practically convenient methods have been developed for the preparation of new iridium complexes, possessing bulky N-heterocyclic carbene and phosphine ligands; these routinely handled complexes are highly active catalysts within directed hydrogen isotope exchange processes.

The synthesis and characterisation of two groups nonsymmetric dimers, the 1-(4-cyanobiphenyl-4‘−yloxy)-ω-(4-butyl, 4-(1-methylpropyl) or 4-t-butylanilinebenzylidene-4’−oxy)alkanes, 1-(4-cyanobiphenyl-4‘−yl)-ω-(4-butyl, are reported. length parity flexible spacer is varied. tert-butyl homologues show higher melting points than corresponding sec-butyl n-butyl substituted suggesting that chain bra...

13-vertex indenyl cobaltacarboranes with 4,1,6-, 4,1,10- and 4,1,2-CoC(2)B(10) architectures have been synthesised by reduction of the corresponding closo carborane and metallation with an {(eta-C(9)H(7))Co} fragment. Variants of the 4,1,6-isomer were prepared with no, one and two methyl groups on cage C atoms, whilst 4,1,2-species were obtained both with two methyl groups and a trimethylene te...

Abstract A reproducible and scalable method has been developed for the synthesis of a series 3,6-substituted pyrazolo[1,5- ]pyrimidines, which are basis rational design selective inhibitors AMP-activated protein kinase. Regarding formation new types carbon skeleton, applicability Suzuki–Miyaura cross-coupling using Buchwald ligands to form C–C bond in sterically hindered position 6 5,7-dimethyl...