Oltipraz is considered one of the most potent cancer chemoprevention agents, as shown in preclinical studies. Its pharmacological effects in humans have been associated with unusual toxicity affecting the fingers and toes. This study was designed to test intermittent dosing schedules using two dosage levels: 500 mg as a single weekly dose and 200 mg as a biweekly dose, each for 30 days. Fifteen...

Introduction and objectives: The diagnosis of malignant and potentially malignant epithelial lesions of the oral mucosa cannot be based solely on clinical findings. Therefore, histologic evaluation of a representative biopsy specimen is necessary. However, the site for the biopsy is always a subjective choice that sometimes raises doubts about its representativeness. Colposcopy, a well-known gy...

Background And Objectives: Oral cavity cancer is a one of the common form of malignancies in the northeastern India. This study was to analyze, treatments and outcomes of oral cancers. Materials And Methods: The study was conducted in the department of Otorhinolaryngology and head Neck Surgery, Assam Medical College and Hospital, Dibrugarh, Assam, India between February 2014 to September 2015. ...

Adenoid cystic carcinomas are deceptive malignancies that show slow growth and local invasion with recurrences seen many years after diagnosis. Upto 50% of these tumors occur in the intraoral minor salivary glands usually in the hard palate. Buccal mucosal tumors are relatively rare. We determined the incidence of buccal mucosal adenoid cystic carcinoma by reviewing the number of reported cases...

introduction: reconstruction of the oral cavity witha flap design containing the buccal mucosa and buccinator muscle but excluding the facial artery and vein is the topic of these case reports. case reports: this article uses random pattern vertically oriented partial thickness buccinator myomucosal flap for intraoral reconstruction in two cases. the first was for lining the mandibular anterior...

Buccal patches are the types of formulations in which drug is administered through buccal mucosa. these or placed between gums and for pharmacological response. The main advantage there no first pass metabolism takes place easily absorb systemic circulation themucosa .the objective this delivery system to elevate increase bioavailability drug. review informs about steps involve preparation patc...