Forward stair climbing (FSC) is associated with cardiovascular fitness benefits, but the training effects of backward stair climbing (BSC) have not been reported in the literature. This study compared the effects of 8 weeks of FSC and BSC on the cardiovascular parameters of apparently healthy young adults. Forty apparently healthy young adults, aged 18-30 years were recruited consecutively and ...

PURPOSE The prognosis of platinum-based chemotherapy-resistant metastatic urothelial cancer of the bladder remains poor. Personalized selection of the right peptides for each patient could be a novel approach for a cancer vaccine to boost anticancer immunity. EXPERIMENTAL DESIGN In this randomized, open-label, phase II study, patients ages ≥18 years with progressive bladder cancer after first...

A bumetanide-sensitive Na-K-2Cl cotransporter, BSC-1, is believed to mediate the apical component of transcellular NaCl absorption in the thick ascending limb (TAL) of Henle's loop. To study its ultrastructural localization in kidney, we used an affinity-purified, peptide-derived polyclonal antibody against rat BSC-1. Immunoblots from rat kidney cortex and outer medulla revealed a solitary 161-...

We examine the association between contingency variables and the adoption of a Balanced Scorecard (BSC). The contingency variables we examine include business-level strategy, firm size, environmental uncertainty, and investment in intangible assets. Utilizing both survey and archival data, collected as part of a mixed-methodology design, we find that BSC adoption is significantly related to bus...

BACKGROUND To compare volume reserve capacity (VRC) and development of intra-abdominal hypertension after different in vitro temporary abdominal closure (TAC) techniques. METHODS A model of the abdomen was designed. The abdominal wall was simulated with polychloroprene, a synthetic rubber compound. A lentil-shaped defect of 150 cm(2) was cut into the anterior aspect of the abdominal wall. TAC...

BACKGROUND After intradural cranial surgery, a dural substitute is often required for dural closure. Although preferred, limitations of autograft include local availability and additional surgical site morbidity. Thus, allografts, xenografts, and synthetics are frequently used. OBJECTIVE To report 6-month results of a randomized, controlled trial of a biosynthesized cellulose (BSC) composed d...

Tissue-mimicking phantoms with high scatterer concentrations were examined using quantitative ultrasound techniques based on four scattering models: The Gaussian model (GM), the Faran model (FM), the structure factor model (SFM), and the particle model (PM). Experiments were conducted using 10- and 17.5-MHz focused transducers on tissue-mimicking phantoms with scatterer concentrations ranging f...

the present study aims to address the problem of inadequate coverage of various aspects of organizational performance by balanced scorecard (bsc) model through its developing based on the european foundation for quality management (efqm) model. to this end, a developed bsc model, encompassing variables of stakeholders, resource effectiveness, processes effectiveness, human resource management e...

strategic performance evaluation of an organization within the industry environment is one of the basic and most important prerequisites of organizational improvement plans. in today’s knowledge-based economy and dynamic environment, it is essential for universities as the centers of education, knowledge creation and knowledge worker evolvement. till now, variant models with different approache...

Blood circulating cell-free DNA (cfDNA) is becoming popular in the search of promising predictive and prognostic biomarkers. Among these biomarkers, cfDNA methylation markers have especially gained considerable attention. A significant challenge in the utilization of cfDNA methylation markers is the limited amount of cfDNA available for analyses; reportedly, bisulfite conversion (BSC) reduce cf...