Mediastinoscopy was carried out in 400 cases, including 296 of bronchogenic carcinoma. At the time of presentation the new growth had already spread to involve the mediastinal lymph nodes in slightly more than 50% of these. The incidence of involvement was 76% in oat-cell and 35% in squamous-cell carcinoma. Non-resectability at thoracotomy was encountered in seven out of 120 patients. We advoca...

The aim of the present study was to examine the epidemiology, natural history, treatment and long-term survival of patients with adenosquamous cell carcinoma of the prostate. The Surveillance, Epidemiology, and End Results (SEER) Program database was used to identify ASCC of prostate cases between January 1973 and December 2006. Survival probabilities were estimated using the Kaplan-Meier metho...

Peripheral blood lymphocytes from patients with bronchogenic carcinoma were tested in microcytotoxicity assays against cultured bronchogenic cancer cells, other types of tumor cells, and skin fibroblasts. Lymphocytes from patients who were postresection with no clinical evidence of residual or recurrent tumor were more frequently toxic against bronchogenic carcinoma than were lymphocytes from n...

BACKGROUND DeltaNp63 is an isoform of the p53 homolog p63, which lacks an amino-terminal transactivation domain. The aim of this study was to detect the deltaNp63 expression in the squamous carcinoma component of adenosquamous carcinoma and evaluate its usefulness as a specific squamous carcinoma marker. PATIENTS AND METHODS Immunohistochemistry was used to analyze the protein expression of d...

Adenosquamous carcinoma colon is a rare neoplasm of colon and is said to have an aggressive course and thus poorer prognosis. Here we have described a case of adenosquamous carcinoma colon in an elderly female patient, presenting with typical features of a colonic malignancy, but with a rapidly deteriorating clinical course and liver metastasis.

Primary cutaneous adenosquamous carcinomas are very rare entities with only few published reports in literature. We describe a primary cutaneous adenosquamous carcinoma found in the occipital region of a 53 year old man with a pediculated tumor of 7 cm in diameter and an ulcerated, verrucous aspect with serous exudations. There was no clinical or radiologic evidence of invasion of the cranial v...

A rectal carcinoma, including primary an adenosquamous and a squamous cell carcinoma (SCC), is a very rare disease, accounting for 0.025% to 0.20% of all large-bowel malignant tumors. Because SCCs have a higher mortality than adenosquamous carcinomas, determining whether the primary rectal cancer exhibits an adenomatous component or a squamous component is important. While differentiating betwe...

BACKGROUND Adenosquamous carcinoma is a rare and aggressive form of lung cancer. The prognostic and predictive value of preoperative serum tumor markers and frequency of EGFR mutations in adenosquamous lung carcinoma are unclear. METHODS We retrospectively analyzed data and samples collected from 106 radically resected adenosquamous lung carcinoma patients with pathological stage I-IIIA betwe...

Given the extended survival of patients diagnosed with cervical cancer, a large number of women are treated with radiotherapy. A second primary cancer has currently become one of the most important radiation-induced injuries as the number of cancer patients who are cured is increasing by virtue of recent advancements in therapeutic radiology. A 56-year-old woman developed two pelvic malignancie...