The galactose-binding lectin from the seeds of the jequirity plant (Abrus precatorius) was subjected to various chemical modifications in order to detect the amino acid residues involved in its binding activity. Modification of lysine, tyrosine, arginine, histidine, glutamic acid and aspartic acid residues did not affect the carbohydrate-binding activity of the agglutinin. However, modification...

The enantiospecific coupling of secondary and tertiary boronic esters to aromatics has been investigated. Using p-lithiated phenylacetylenes and a range of boronic esters coupling has been achieved by the addition of N-bromosuccinimide (NBS). The alkyne functionality of the intermediate boronate complex reacts with NBS triggering the 1,2-migration of the group on boron to carbon giving a dearom...

Abstract A boron trifluoride catalysed reaction of coplanar 9-(phenyl­ethynyl)-9H-fluoren-9-ols with various 2-aminobenzamides affords a number highly functionalized, conjugated (Z)-2-((2-(9H-fluoren-9-ylidene)-1-phenylethylidene)amino) benzamides in excellent yield. The the presence N-bromosuccinimide (E)-5-bromo-2-((2-bromo-2-(9H-fluoren-9-ylidene)-1-phenylethylidene)amino)benz­amides very go...

A simple indirect spectrophotometric method for determination of mebendazol in pure and pharmaceutical formulation was presented this study. UV-Visible spectrophotometry using the optimal conditions developed mebendazole drug different preparation samples. The is based on oxidation by n-bromosuccinimide with hydrochloric acid left amount oxidizing agent determined reaction tartarazine absorbanc...

Reaction of N-bromosuccinimide with ammonium salt of alkylene (dialkyl) dithiophosphates, [OGOPS(2)NH(4); G=-CMe(2)CMe(2)-CH(2)CMe(2)CH(2)-, CMe(2)CH(2)CHMe(2)-, CH(2)CH(2)CHMe(2)-; (RO)(2)PS(2)NH(4); R=C(2)H(5), n-C(3)H(7), i-C(3)H(7)], in 1 : 1 molor ratio in refluxing benzene solution yields red/brown-colored sticky liquids. These newly synthesized complexes have been characterised by physic...

Modification of tryptophan side chains of soybean agglutinin (SBA) with N-bromosuccinimide results in a loss of the hemagglutinating and carbohydrate binding activities of the protein. One residue/subunit is probably essential for the binding activity. Modification leads to a large decrease in the fluorescence of the protein accompanied by a blue shift. Iodide ion quenching of the protein fluor...