نتایج جستجو برای: bromomethyl 1
تعداد نتایج: 2752724 فیلتر نتایج به سال:
Crystal structure of rel-(2R,3aS)-2-bromomethyl-3,3a,4,5,6,7-hexahydro- 2H-indole 1-oxide, C9H14BrNO
2-monobromomethyl 1,4-dihydropyridines is selectively synthesized by bromination of the parent compound by 1.1 equivalents of pyridinium bromide perbromide in dichloromethane/pyridine at -20 °c. the same reagent in dichloromethane at 0 °c produce the 2,6-bis(bromomethyl) 1,4-dihydropyridines.
A method previously developed for the regiospecific synthesis of polysubstituted indolines and indoles has been investigated for its utility in organic synthesis. The method relies on the regiospecific generation of zirconocene-stabilized benzyne complexes from N-allyl-2-bromoaniline derivatives. These complexes undergo an intramolecular olefin insertion to provide 5,5,6-tricyclic indoline zirc...
BACKGROUND It is seen that the regioselective functionalizations of halogenated heterocycles play an important role in the synthesis of several types of organic compounds. In this domain, the Suzuki-Miyaura reaction has emerged as a convenient way to build carbon-carbon bonds in synthesizing organic compounds. Some of the most important applications of these reactions can be seen in the synthes...
Pro-Val pseudo dipeptides incorporating protio and halo enol lactones were tested for inhibitory activity against the serine proteases human leukocyte elastase (HLE), porcine pancreatic elastase, alpha-chymotrypsin, trypsin, thrombin, and urokinase. The protio enol lactones 1a-c were found to be HLE substrates but were poor alternate substrate inhibitors. The bromo enol lactone trans isomer 2a ...
Adamantyl-based compounds are commercially important in the treatments for neurological conditions and type-2 diabetes, aside from their anti-viral abilities. Their values in drug design are chronicled as multi-dimensional. In the present study, a series of 2-(adamantan-1-yl)-2-oxoethyl benzoates, 2(a-q), and 2-(adamantan-1-yl)-2-oxoethyl 2-pyridinecarboxylate, 2r, were synthesized by reacting ...
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