This work aims to provide sampling of halogen-containing aniline podophyllum derivatives and their mode of action with an in-depth comparison among fluorine, chloride and bromide for clarifying the important role and impact of fluorine substitution on enhancing antitumor activity, with an emphasis on the development of drug rational design for antitumor drug. The tumor cytotoxicity of fluoride-...

Surfaces of a Wyoming SWy-2 sodium montmorillonite were modified using microwave radiation through intercalation with the cationic surfactants octadecyl-trimethyl ammonium bromide, dimethyldioctadecylammonium bromide, and methyl-tri-octadecyl ammonium bromide by an ion exchange mechanism. Changes in the surfaces and structure were characterized using X-ray diffraction (XRD), thermal analysis (T...

Ultrasonic velocities in solution of tetrabutylammonium bromide (TBAB) in 10, 20 and 30 %w/w N, N– dimethylformamide (DMF)-water mixtures were measured at 303 K, 308 K and 313 K by using the pulse echo overlap method at a frequency of 3 MHz. The ultrasonic velocity, density, and viscosity were used to calculate the adiabatic compressibility, apparent molal compressibility, apparent molal volume...

The asymmetric unit of the title hydrated salt, C15H37N6 (3+)·2Br(-)·OH(-)·H2O, contains one cation, three partial-occupancy bromide ions, one hydroxide ion and one water mol-ecule. Refinement of the site-occupancy factors of the three disordered bromide ions converges with occupancies 0.701 (2), 0.831 (2) and 0.456 (2) summing to approximately two bromide ions per formula unit. The structure w...

The kinetics of chloride and bromide transport were examined in intact human red blood cells and resealed ghosts. Because the influx and efflux of halide ions are almost equal (less than 0.01% difference), the stimulation of the exchange flux by external halides could be determined by measuring 36Cl or 82Br efflux. When the external halide concentration was increased by replacement of isoionic,...

In the title compound, [ZnBr(2)(C(17)H(14)Cl(4)N(2))], the Zn(II) ion is bonded to two bromide ions and two N atoms of the diimine ligand and displays a moderately distorted tetra-hedral coordination geometry. The Schiff base ligand acts as a chelating ligand and coordinates to the Zn(II) atom via two N atoms.