Objective. Panic attack is defined as specific, frightening experience of intense fear and impending catastrophe that accompanied by numerous somatic symptoms. The scope study was to show the presentation panic disorder in patients EMS Belgrade Ambulatory Clinic, its frequency, temporal patterns prescribed therapy. Methods. research a cross-sectional work one general practitioner gerontology su...

A simple and high-throughput method to simultaneously determine selected benzodiazepines (i.e., diazepam, lorazepam, clonazepam, and bromazepam) in urine was developed and validated. The entire methodology consisted of the application of an innovative extraction/cleanup procedure, namely liquid-liquid extraction with low-temperature partitioning (LLE-LTP), and analysis by liquid chromatography ...

A rapid, simple, highly sensitive procedure for the simultaneous analysis of bromazepam, alprazolam, clonazepam, lorazepam, oxazepam, diazepam, midazolam, flurazepam, flunitrazepam, nordiazepam, triazolam, temazepam, nitrazepam, and chlordiazepoxide in oral fluid is described, using liquid chromatography coupled to a triple quadrupole mass spectrometer in positive electrospray mode. Benzodiazep...

Chronic tinnitus is characterized by neuroplastic changes of the auditory cortex. A promising method for therapy of chronic tinnitus is vagus nerve stimulation (VNS) combined with auditory stimulation. The principle of VNS is reversal of pathological neuroplastic changes of the auditory cortex toward physiological neural activity and synchronicity. The VNS mechanism of action in chronic tinnitu...

Tetrazepam is a benzodiazepine that is widely used in Spain as a muscle relaxant, with occasional cutaneous side effects. We report a patient who developed a generalized pruriginous cutaneous reaction compatible with acute generalized exanthematous pustulosis (AGEP) due to tetrazepam. Patch tests with bromazepam, diazepam, and tetrazepam were negative at 48 and 72 hours; however, the tetrazepam...

A população mundial cresce a cada dia e dados da OMS revelam que cerca de 45% sofre com insônia segundo Fiocruz brasileira também esse mal. pode variar acordo severidade, frequência duração, interferindo diretamente na qualidade do sono. melatonina é um hormônio produzido glândula pineal, tendo sua biossíntese o aminoácido triptofano. vem sendo muito usada no combate insônia, juntamente seu per...