RESPIRATORY GAS EXCHANGE PHYSIOLOGY began with the description of oxygen and carbon dioxide exchange in a one-compartment lung, followed decades later by investigation of the effects of heterogeneity. Those studies were followed by experiments utilizing multiple intravenously infused inert gases of varying blood solubility to further investigate ventilation-perfusion heterogeneity. More recentl...

Sucrose breath hydrogen tests were performed on 7 children with proved sucrase isomaltase deficiency. All children had raised breath hydrogen excretion. The amount of hydrogen produced and symptoms experienced increased with increasing sucrose loads. The sucrose breath hydrogen test appears to be a reliable indicator of sucrose malabsorption in sucrase isomaltase deficiency.

TO THE EDITOR: With great interest we have been following the discussion about our study published in Journal of Neurogastroenterology and Motility. 1 We highly estimate the recent constructive comments expressed by the authors Erdogan and colleagues 2 and would like to make some conclusive remarks. We fully agree with the authors that all patients with irritable bowel syndrome (IBS)-like sympt...

OBJECTIVE To evaluate the incidence of small bowel bacterial overgrowth (SBBO) in children treated with omeprazole, and to test whether probiotics influence the incidence. METHODS A double-blinded, placebo-controlled trial was performed in 70 children treated orally during four weeks with 20mg omeprazole per day. Lactobacillus rhamnosus R0011 (1.9×10(9) cfu) and Lactobacillus acidophilus R005...

Background: The prevalence of Helicobacter pylori (H. pylori) infection in patients with rosacea is reported from 50 to 90 percent, which suggests the possibility of the role of this organism in pathogenesis of rosacea. Objectives: Evaluation of relationship between H. pylori infection and rosacea. Patients and Methods: In this case-control study, 30 patients referred to skin clinics of B...

Objective: Helicobacter pylori (H. pylori) is the most common pathogenic bacteria in the stomach. The aim of the current study was to explore the effect of oral garlic administration on bacterial urease activity inside the stomach and its contribution to the treatment of H. pylori infection.   Materials and Methods: In this clinical trial, 15 patients were studied quantitatively with Urease Bre...

Breast cancer is accompanied by increased oxidative stress and induction of polymorphic cytochrome P-450 mixed oxidase enzymes (CYP). Both processes affect the abundance of volatile organic compounds (VOCs) in the breath because oxidative stress causes lipid peroxidation of polyunsaturated fatty acids in membranes, producing alkanes and methylalkanes which are catabolized by CYP. We performed a...

BACKGROUND Helicobacter pylori infection is the most common gastrointestinal bacterial disease worldwide. Although using culture is considered as the golden standard method for diagnosis of H. pylori infection, urea breath test is a notable alternative method because it is an easy, quick, and non-invasive approach. The aim of this study was to estimate the prevalence of H. pylori infection in p...

This prospective study assessed the role of aminopyrine breath test in the prognosis of patients with cirrhosis, and evaluated whether the test provided useful information not included in the Pugh score. During a period of 36 months, 125 patients with biopsy proven liver cirrhosis were included, and followed for up to 48 months (median 17 months). During follow up 43 patients died (20 of liver ...