MRI is well established in the diagnosis of female breast cancer, with an important role as a problem-solving tool in the postoperative breast and in implant evaluation. Little in the literature mentions the use of MRI in male breast cancer, with there is no clear role for its use at present. We present an unusual case of bilateral male breast carcinoma and demonstrate a similar enhancement pat...

CONTEXT Breast magnetic resonance imaging (MRI) has been shown to have high sensitivity for cancer detection and is increasingly used following mammography to evaluate suspicious breast lesions. OBJECTIVE To determine the accuracy of breast MRI in conjunction with mammography for the detection of breast cancer in patients with suspicious mammographic or clinical findings. DESIGN, SETTING, A...

The utility of MRI in the detection of breast cancer has evolved over the last few decades. It is now the most sensitive imaging tool available for the diagnosis of invasive breast cancer. There are drawbacks however, namely increased cost in comparison to screening mammography and decreased specificity. Thus, it is important to tailor the use of breast MRI to specific screening populations in ...

Background: The monoclonal antibody, C595, against breast cancer cell line was conjugated with cyclic anhydride gadolinium-diethylenetriaminepenta-acetic acid (Gd-cDTPAa) to produce Gd-DTPA-C595 and used as specific breast cancer cell line (MCF-7) contrast agents in magnetic resonance imaging (MRI).  Methods: After incubation of breast cancer cell line (MCF-7), with different contrast agents (G...

The appropriate application of breast MRI in the pre-operative evaluation of women with a new diagnosis of breast cancer is currently one of themost debated and controversial issues in breast cancer management. While it initially seemed clear tomany that MRI’s superior detection capability relative to conventional breast imaging1,3,4,6 for both the affected breast, and the contralateral breast,...

CONTEXT Women with inherited BRCA1/2 mutations are at high risk for breast cancer, which mammography often misses. Screening with contrast-enhanced breast magnetic resonance imaging (MRI) detects cancer earlier but increases costs and results in more false-positive scans. OBJECTIVE To evaluate the cost-effectiveness of screening BRCA1/2 mutation carriers with mammography plus breast MRI compa...

BACKGROUND The American Cancer Society (ACS) guidelines for screening with breast magnetic resonance imaging (MRI) recommend MRI for women who have a lifetime risk > or = 20% of developing breast cancer. Genetic testing for breast cancer gene (BRCA) mutations is offered to women who have a risk > or = 10% of carrying a mutation. The objectives of the current study were 1) to identify the number...

Background: Breast MRI is the most accurate method for evaluating treatment response in breast cancer patients receiving neoadjuvant chemotherapy (NAC). Methods: In this review, the current knowledge with respect to response monitoring of breast cancer patients receiving NAC using MRI is presented. Both standard and more advanced approaches are discussed, including potential pitfalls and future...

INTRODUCTION The aim of this study was to assess the performance and value of breast ultrasound in women with familial risk of breast cancer. MATERIALS AND METHODS From an initial dataset of 245 women with positive family history who had breast cancer surveillance utilising mammography or magnetic resonance imaging (MRI) between November 1994 and February 2001, 179 subjects with follow-up dat...

As breast magnetic resonance imaging (MRI) is being used more frequently to screening and diagnosis of breast malignancies, we often encounter various breast skin lesions appearing as skin thickening or enhancement. Although numerous studies have reported about the breast parenchymal lesions, the dermal lesions of the breast have largely been overlooked. The breast skin lesions may be incidenta...