abstract bachground and aim: mutation analysis of mitochondrial genome and brca genes are helpful in the early diagnosis of familial breast cancers. in this study, we investigated mitochondrial common deletion and brca mutations through multiplex pcr and clinical parameters for the detection of familial breast cancers in archival breast cancer samples. methods: the multiplex pcr was conducted o...

one out of eight women face with the problem of breast cancer in her life. it is the second causes of women death in the world. detection of breast cancer metastasis at the earliest stage is important to predict and control of breast cancer progression. it can spread to the different parts of the body, such as are the bone, liver, and lung and etc. how and where does the breast metastasis grow ...

background: clinical experiences have revealed that patients with breast cancer experience various sexual problems following their treatment. breast cancer negatively impacts the sexual life of the afflicted couples, and as a traumatic event can influence women’s psychosexual functioning and intimate relationship. this review focuses on sexuality after breast cancer and on a growing need for bi...

background: potential association of leptin (lep) gene polymorphisms has been suggested in the processes leading to breast cancer initiation and progression. we investigated whether genetic variations in the lep -2548g/a gene are associated with risk of breast cancer. methods: this case-control study consisted of 100 breast cancer cases and 100 control subjects without breast cancer that matche...

mri of the breast has evolved as a non-invasive imaging modality and is ideally suited for several indications e.g. pre-operative staging and screening in women at increased risk for breast cancer. the widespread use opens also the discussion on over-diagnosis if only 20 - 30 out of 100 mri - guided breast biopsies lead to the diagnosis of breast cancer. thus mri based strategies are needed to ...

the male breast cancer (mbc) is a very rare neoplasm which accounts for 0.5-1% of the total cases of breast cancer. bilateral involvement is reported to occur in fewer than 2% of all the diagnosed cases of mbc, and synchronous tumors are very rare. because of its rarity, little is known about mbc etiology, its clinical findings and treatment. most patients present with a painless breast mass. t...

background: breast cancer is the most common type of malignancy in the female population, rarely is reported by thromboembolic events during the course of the disease. in this case, we present a rare case of breast cancer presenting as deep vein thrombosis of the axillary vein.case presentation: a 40-year- old female was admitted due to pain and swelling of her right arm and forearm of two mont...