Water-soluble fluorescent copper, silver and gold nanoclusters with quantum yields of 2.2, 6.8 and 5.3%, respectively, are prepared by a robust photoreduction of their inorganic precursors in the presence of poly (methacrylic acid) functionalized with pentaerythritol tetrakis 3-mercaptopropionate.

Gold nanorods are effective photothermal agents in diagnosis and treatment of cancer due to their specific near-infrared laser absorption. However, tumor photothermal therapy by nanorods alone is lack of targeting. Here, we described a novel nanocomplex made up of gold nanorods, porphyrin, and trastuzumab, called TGNs and investigated the TGN-mediated photothermal therapy as a potential alterna...

A one-step microwave-assisted method is used for the synthesis of small gold nanoclusters, Au(16)NCs@BSA, which are used as a fluorescence enhanced sensor for detection of silver(I) ions with high selectivity and sensitivity.

A series of gold(I) and gold(III) complexes with N-heterocyclic carbene ligands functionalized a pendant thioether group (NHC-SR) was synthesized straightforward procedures characterized in solution NMR spectroscopy ESI-MS spectrometry, as well the solid state by means single crystal X-ray diffraction analysis. Selected experimental aspects were rationalized through relativistic DFT calculation...

Multifunctional nanoprobes have great potential as effective radiosensitizers and drug carriers. RGD-modified gold nanorods could increase the uptake of nanoparticles via receptor-mediated endocytosis in integrin alphaV beta3-overexpressing breast cancer cells, which could enhance the effects of radiation on tumor cells, leading to further radiosensitization. The purpose of our study was to dem...

background: exposure to endogenous hormones such as estrogen is known as a lifetime breast cancer (bc) risk factor. polymorphisms in genes that are involved in the steroidogenic process, such as cytochrome p450c17alpha ( cyp17) , affect individuals’ susceptibility to bc. in iran, the highest incident of bc is among young women. this study aimed to find prevalence of single nucleotide polymorphi...

In the war against cancer, two cytotoxic metallic fragments—gold and platinum, symbolically represented as superheroes—join forces in a single molecule. Our research showcases impressive potency of these molecules panel cancer cell lines, with an emphasis on 2D 3D triple negative breast models. More information can be found Research Article by M. Contel co-workers (DOI: 10.1002/chem.202302045).

Relative stability of geometric magic-number gold nanoclusters with high point-group symmetry ((Ih), D(5h), O(h)) and size up to 3.5 nm, as well as structures obtained by global optimization using an empirical potential, is investigated using density functional theory (DFT) calculations. Among high-symmetry nanoclusters, our calculations suggest that from Au(147) to Au(923), the stability follo...

In a recent study, we found that nematic liquid crystals (N-LCs) doped with chiral (S)-naproxenfunctionalized dodecane thiolate protected gold nanoclusters (Au2, Au3) or non-chiral alkyl thiolate protected Au clusters (Au1) produce thin film textures with characteristic uniform stripe patterns separated by areas of homeotropic alignment. While these textures closely resemble textures commonly o...