breast cancer affects iranian women at least one decade younger than their counterparts in othercountries and the incidence of breast fibroadenoma is growing in the last two decades in tehran. thisstudy aimed to compare the ahr levels in premenopausal breast cancer and breast fibroadnemo withappropriate normal groups. possible associations of ahr with lifestyle and reproductive risk factorsand ...

conclusions in this study, we proposed a new computer aided diagnostic tool for the detection and classification of breast cancer. the obtained results showed that the proposed method is more reliable in diagnostic to assist the radiologists in the detection of abnormal data and to improve the diagnostic accuracy. results after classification with the ensemble supervised algorithm, the performa...

background: metformin is used to lower blood sugar in patients with type ii diabetes. recent research showed that metformin has effects on cancer cell growth. studies show that metformin can induce apoptosis in certain cancer cell lines. in this study, we examined the effect of metformin on apoptosis in the t47d breast cancer cell line. methods : the t47d breast cancer cell line was selected an...

background: regulatory t cells (t-regs) have an important role in cancer by suppression of protective antitumor immune responses. regulatory t cells express the forkhead/winged helix transcription factor (foxp3) and ox40 molecules which have important regulatory roles in the immune system. objective: to evaluate foxp3 and ox40 transcripts in the peripheral blood mononuclear cells of women with ...

accounts for 27% of all cancers. according to the national cancer institutes' reports, the risk of breast cancer among american women is 13%. the current study aims to evaluate the level of risk perception of breast cancer and to identify its related factors amongst female employees. methods: this project was a cross-sectional study and participants were female employees working in hospitals an...

background: breast cancer is the most common malignancy in females worldwide. several etiological factors including environmental factors have been recognized for breast cancer. epstein barr virus as a viral etiological factor has been proposed. so far, several studies have investigated the relationship between development of breast cancer and epstein barr virus, but few have been done in iran....

objective(s):this study aims to investigate the relationship between human papillomavirus (hpv) and breast cancer using meta- analysis. materials and methods: relevant studies were identified reviewing the national and international databases. we also increased the search sensitivity by investigating the references as well as interview with research centers and experts. finally, quality assessm...

background: pharmacogenomics is the study of genetic variations among individuals to predict the probability that a patient will respond to single or multidrug chemotherapy. breast cancer is one of the most common cancers among women worldwide. treatment of breast cancer by application of biological rationales gives us the ability to match the correct pharmacology to individual tumour genetic p...