Background: Maple syrup urine disease (MSUD) is an inherited branched-chain amino acid metabolic disorder caused by the deficiency in the branched-chain alpha-keto acid dehydrogenase (BCKD) complex. In MSUD, elevation of the branched-chain amino acids, such as alpha-keto acid and alpha-hydroxy acid, occurs due to the BCKDC gene deficiency, appearing in the blood, urine, and cerebrospinal fluid,...

We present a tool which supports CT specialists in exploring the parameter and result space of volume segmentation pipelines. In a preprocessing step, the user samples the parameter space of a number of pipelines to be analysed. Our sampling tool supports arbitrary pipeliness that can be parametrized via the command line. The user can then explore the space of possible results of the sampled pi...

Summary We designed a PyQt graphical user interface - Sequanix - aimed at democratizing the use of Snakemake pipelines in the NGS space and beyond. By default, Sequanix includes Sequana NGS pipelines (Snakemake format) (http://sequana.readthedocs.io), and is also capable of loading any external Snakemake pipeline. New users can easily, visually, edit configuration files of expert-validated pipe...

High performance processors based on pipeline processing play an important role in scientific and engineering computation. However, it is difficult to gain a satisfactory solution when taking both high degree of flexibility of parallel processing and low hardware complexity into account. This paper propose a hybrid pipeline architecture named Jetpipeline that possesses high degree of flexibilit...

Pipeline networks are one of the key infrastructures of our modern life. Proactive monitoring and frequent inspection of pipeline networks are very important for sustaining their safe and efficient functionalities. Existing monitoring and maintenance approaches are costly and inefficient because pipelines can be installed in large scale and in an inaccessible and hazardous environment. To overc...

Underground oil pipelines are made of pressurized pipes, and when damage occurs, the consequences can be disastrous. Pipeline accidents caused by stress can be attributed to material corrosion, impractical design, manufacturing defect, environmental damage, and man-made destruction. In this study, by utilizing the stress analysis software CAESAR II, the stress of pipelines in high and steep slo...

Many of the typical tasks in linguistic processing pipelines can be done with tools from OpenNLP (http://opennlp.sourceforge.net). There are OpenNLP components for sentence detection, tokenization, part-of-speech tagging, phrase chunking, syntactic parsing, named entity recognition, and coreference resolution. These tools have been widely used for several years, and form a good basis for illust...

Are Two Motor-Control Systems Better Than One? Kyle Reed, Michael Peshkin, Mitra J. Hartmann, Marcia Grabowecky, James Patton, and Peter M. Vishton Department of Mechanical Engineering, Northwestern University; Department of Biomedical Engineering, Northwestern University; Department of Psychology, Northwestern University; Rehabilitation Institute of Chicago, Chicago, Illinois; and Department o...

.............................................................................................................................. ii Dedication .......................................................................................................................... iv Acknowledgments............................................................................................................... v T...