نتایج جستجو برای: brain white matter

تعداد نتایج: 816563  

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2017
Karen Hodgson Melanie A Carless Hemant Kulkarni Joanne E Curran Emma Sprooten Emma E Knowles Samuel Mathias Harald H H Göring Nailin Yao Rene L Olvera Peter T Fox Laura Almasy Ravi Duggirala John Blangero David C Glahn

The accurate estimation of age using methylation data has proved a useful and heritable biomarker, with acceleration in epigenetic age predicting a number of age-related phenotypes. Measures of white matter integrity in the brain are also heritable and highly sensitive to both normal and pathological aging processes across adulthood. We consider the phenotypic and genetic interrelationships bet...

2009
Harris A. Ngow Wan Mohd Nowalid Wan Khairina Bin Basri Hamidon

Brain edema in patients with hypertensive encephalopathy frequently affects the parietooccipital white matter. Hypertensive encephalopathy is thus included as a differential diagnosis in reversible posterior leukoencephalopathy syndrome. Diffuse white matter involvement rarely occurs. We report a 41-year old woman with hypertensive encephalopathy with diffuse and non-enhancing white matter hype...

Journal: :Journal of the mechanical behavior of biomedical materials 2015
Silvia Budday Richard Nay Rijk de Rooij Paul Steinmann Thomas Wyrobek Timothy C Ovaert Ellen Kuhl

The mammalian brain is composed of an outer layer of gray matter, consisting of cell bodies, dendrites, and unmyelinated axons, and an inner core of white matter, consisting primarily of myelinated axons. Recent evidence suggests that microstructural differences between gray and white matter play an important role during neurodevelopment. While brain tissue as a whole is rheologically well char...

Journal: :AJNR. American journal of neuroradiology 1999
R Ashikaga Y Araki Y Ono Y Nishimura O Ishida

BACKGROUND AND PURPOSE Fluid-attenuated inversion-recovery (FLAIR) MR imaging is widely accepted for brain diagnoses, though to our knowledge no description of the MR FLAIR appearance of the normal infantile brain has been published. The purpose of this study was to investigate the appearance of normal infantile brain maturation on FLAIR MR images. METHODS FLAIR images were obtained in 52 chi...

Journal: :Cerebral cortex 2012
Megan M Herting Emily C Maxwell Christy Irvine Bonnie J Nagel

BACKGROUND During adolescence, numerous factors influence the organization of the brain. It is unclear what influence sex and puberty have on white matter microstructure, as well as the role that rapidly increasing sex steroids play. METHODS White matter microstructure was examined in 77 adolescents (ages 10-16) using diffusion tensor imaging. Multiple regression analyses were performed to ex...

Journal: :Journal of neurosurgery 2002
Brian P Witwer Roham Moftakhar Khader M Hasan Praveen Deshmukh Victor Haughton Aaron Field Konstantinos Arfanakis Jane Noyes Chad H Moritz M Elizabeth Meyerand Howard A Rowley Andrew L Alexander Behnam Badie

OBJECT Preserving vital cerebral function while maximizing tumor resection is a principal goal in surgical neurooncology. Although functional magnetic resonance imaging has been useful in the localization of eloquent cerebral cortex, this method does not provide information about the white matter tracts that may be involved in invasive, intrinsic brain tumors. Recently, diffusion-tensor (DT) im...

Journal: :Archives of general psychiatry 1990
G Fein C Van Dyke L Davenport B Turetsky M Brant-Zawadzki L Zatz W Dillon P Valk

Although deep white-matter brain lesions are seen on magnetic resonance imaging in about one third of elderly subjects, their clinical significance is not known. In 1984, we studied three retired teachers who had extensive deep white-matter brain lesions on magnetic resonance imaging, yet functioned cognitively at an above-average level. Blinded review of 1981 computed tomographic scans reveale...

2017
Peter McColgan Kiran K. Seunarine Sarah Gregory Adeel Razi Marina Papoutsi Jeffrey D. Long James A. Mills Eileanoir Johnson Alexandra Durr Raymund A.C. Roos Blair R. Leavitt Julie C. Stout Rachael I. Scahill Chris A. Clark Geraint Rees Sarah J. Tabrizi the Track-On HD Investigators

We lack a mechanistic explanation for the stereotyped pattern of white matter loss seen in Huntington's disease (HD). While the earliest white matter changes are seen around the striatum, within the corpus callosum, and in the posterior white matter tracts, the order in which these changes occur and why these white matter connections are specifically vulnerable is unclear. Here, we use diffusio...

Journal: :Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1988
M Kirikae M Diksic Y L Yamamoto

An autoradiographic method for the measurement of the rate of valine incorporation into brain proteins is described. The transfer coefficients for valine into and out of the brain and the rate of valine incorporation into normal rat brain proteins are given. The valine incorporation and the transfer constants of valine between different biological compartments are provided for 14 gray matter an...

2016
Sheng Xie Zhe Zhang Feiyan Chang Yishi Wang Zhenxia Zhang Zhenyu Zhou Hua Guo

Subcortical white matter builds neural connections between cortical and subcortical regions and constitutes the basis of neural networks. It plays a very important role in normal brain function. Various studies have shown that white matter deteriorates with aging. However, due to the limited spatial resolution provided by traditional diffusion imaging techniques, microstructural information fro...

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