Scanning of the radioactive tracers in the calvarium represents a major advance of diagnostic techniques in the evaluation of intracranial disease. The pioneering work by Moore (18) at Mayo Clinic in 1948 utilized 1311 labeled Di-lodo-fluorescein as the tracer detected by a Geiger-Muller tube. This now primitive system demonstrated a higher concentration of the isotope tracer in the brain tumor...

background: choriocarcinoma is a rare highly malignant trophoblastic neoplasm. it can be preceded by any form of gestation including a complete or a partial mole, miscarriage and normal pregnancy. simultaneous intraplacental choriocarcinoma involving both mother and infant is extremely rare. hepatomegaly, anemia, elevated ßhcg is the diagnostic triad. here we report a 6 weeks old afghan girl in...

speech delay with an unknown cause is a problem among children. this diagnosis is the last differential diagnosis after observing normal findings in routine hearing tests. the present study was undertaken to determine whether auditory brainstem responses to click stimuli are different between normally developing children and children suffering from delayed speech with unknown causes. in this cr...

the current study was performed with the aim of investigating the diagnostic utility of bender-gestalt test-ii (bdt-ii) in two groups of patients with major depression and brain-damage, and to compare them with normal individuals. this was a causal-comparative study. major depressive patients (n=30), brain-damaged patients (n=30) and normal subjects (n=30) were compared using bdt-ii in copying,...

in this paper an automatic examination robot was developed to improve the process of cancer detection, tumor localization and geometrical shape diagnosis. a uniformly distributed compressive load was applied to the top tissue surface and the resultant mechanical stress was measured that was employed for the tumor diagnosis task. the experimental examinations were performed on the soft tissue of...

background: the humbug gene is a truncated isoform of aspartyl β-hydroxylase (asph) gene that is overexpressed in many human malignancies. in recent years, since humbug has received increasing attention, it is considered as a potential therapeutic molecular target. therefore, it is necessary for preparing humbug protein and its monoclonal antibody to investigate its structure and function. meth...

background and importance: the coexistence of pituitary adenoma and another type of brain tumor is a very rare clinical scenario. even though such a presentation can be an incidental event but the possible pathogenesis of coexistence of different lesions in the sella and suprasellar region has not yet been elucidated. case presentation: two cases of concomitant sellar and suprasellar region tum...

how to cite this article: tabatabaei sm, seddighi a, seddighi as. posterior fossa tumor in children. iran. j. child. neurol 2012;6(2): 19-24.   objective primary brain tumors are the most common solid neoplasms of childhood, representing 20% of all pediatric tumors. the best current estimates place the incidence between 2.76 and 4.28/100,000 children per year. compared with brain tumors in adul...

objective(s): in order to grow cells in a three-dimensional (3d) microenvironment, self-assembling peptides, such as puramatrix, have emerged with potential to mimic the extracellular matrix. the aim of the present study was to investigate the influence of the self-assembling peptide on the morphology, survival, proliferation rate, migration potential, and differentiation of human meningioma st...

objective(s): the study objective was to assess the diagnostic performance of positron emission tomography (pet) for gliomas using the novel tracer 18f-fluciclovine (anti-[18f]facbc) and to evaluate the safety of this tracer in patients with clinically suspected gliomas.methods: anti-[18f]facbc was administered to 40 patients with clinically suspected high- or low-grade gliomas, followed by pet...