BACKGROUND Serum N-terminal pro-brain natriuretic peptide (NT-proBNP) is regarded as a sensitive marker of cardiovascular disease. Vascular disease plays an important role in cognitive impairment. METHOD In 447 elderly patients with mental illness, serum NT-proBNP level and the presence or absence of vascular disease according to the medical record were used to categorize patients in differen...

Objective: To evaluate whether measurements of N-terminal pro-brain natriuretic peptide (NT-proBNP) can be used to differentiate patients with normal and reduced left ventricular ejection fraction (LVEF) in an unselected consecutive group of hospital inpatients. Setting: City general hospital, Copenhagen, Denmark. Patients and design: During a 10 month period 2230 admissions to a city general h...

BACKGROUND The prognostic value of natriuretic peptide elevations in patients with acute coronary syndromes (ACS) is still incompletely defined. We measured N-terminal pro-brain natriuretic peptide (NT-proBNP) on admission in patients with ACS and ECG evidence of myocardial ischemia. METHODS AND RESULTS The NT-proBNP was measured at a median time of 3 hours after symptom onset in 1756 patient...

Right ventricular systolic dysfunction (RVSD) at baseline (pre-treatment) predicts early death in patients with pulmonary hypertension (PH). However, RVSD can only be detected reliably by prohibitively invasive or expensive techniques. N-terminal B-type natriuretic peptide concentration ([NT-proBNP]) correlates with RV function in PH; however, an [NT-proBNP] threshold that indicates RVSD in ind...

n-terminal pro β-type natriuretic peptide (nt-probnp) is a valuable marker for monitoring the response to treatment in patients with heart failure. based on the clinically observed improvement of heart failure symptoms early after cardiac resynchronization therapy (crt), we sought to investigate whether crt induce any significant reduction in the plasma level of nt-probnp in three days after im...

OBJECTIVE To evaluate whether measurements of N-terminal pro-brain natriuretic peptide (NT-proBNP) can be used to differentiate patients with normal and reduced left ventricular ejection fraction (LVEF) in an unselected consecutive group of hospital inpatients. SETTING City general hospital, Copenhagen, Denmark. PATIENTS AND DESIGN During a 10 month period 2230 admissions to a city general ...

ObjectiveThe purpose of this study was to evaluate the protective effect Shengmai Zhenwu decoction on patients with chronic heart failure (CHF) based levels soluble interleukin 1 receptor-like (ST2).MethodsWe included a total 80 outpatients and inpatients CHF who were undergoing treatment at Shanghai Municipal Hospital Traditional Chinese Medicine between March 2020 2022. We randomly divided th...

A large number of experimental studies have suggested that hypoxia may be a potent stimulus for the myocardial synthesis and release of Atype natriuretic peptide (ANP) and B-type natriuretic peptide (BNP) [1]. However, these studieshaveevaluatedeither theeffectofhypoxiaonANP and/orBNPproduction in isolated cardiomyocytes [2,3], isolatedperfused hearts [4,5], or animals [5,6], or on the circulat...

can predict cardiac failure after cardiac surgery. Circ J 2007; 71: 79–83 20 Kerbaul F, Giorgi R, Oddoze C, et al. High concentrations of N-BNP are related to non-infectious severe SIRS associated with cardiovascular dysfunction occurring after off-pump coronary artery surgery. Br J Anaesth 2004; 93: 639–44 21 Guerin V, Ayed SB, Varnous S, et al. Release of brain natriuretic-related peptides (B...

BACKGROUND/AIMS Brain natriuretic peptide is a cardiac neurohormone secreted from ventricles in response to end diastolic pressure and increased volume. It has diuretic, natriuretic and vasodilator effects. In cirrhosis, a hyperdynamic circulation occurs because of hemodynamic and hemostatic alterations. The increase in brain natriuretic peptide concentration shows parallelism with the stage of...