Lipid peroxidation (LPO), an oxidative chain reaction often occurring in the human body and food, is harmful to health. Due its convenience low cost, this guideline highlights benefits drawbacks of LPO models by spectrophotometer vitro vivo. The preparation process mechanism lipid substrates, oxidation triggers detection methods are discussed paper better screen antioxidants. substrates mostly ...

Abstract Alzheimer’s disease (AD) is a multifactorial neurodegenerative central system with high prevalence among the elderly and most common form of dementia. Oxidative stress crucial on AD pathogenesis leads to deposition neurofibrillary tangles Aβ plaques; therefore, use natural antioxidants or ROS scavengers could help avoid formation these aggregates. Similarly, Aβ-degrading/anti-aggregati...

The erythrocyte levels of the antioxidant enzymes SOD and GPx, and serum levels of antioxidants vitamins β-carotene and β­ tocopherol were estimated in various types of brain tumors, and were compared with the levels in controls. Statistically significant (P<.001) diminished levels of βcarotene, β-tocopherol, SOD and GPx, were observed in all the brain tumor patients as compared to controls. Ma...

The current review is informed about the effectiveness of plant-derived functional components that aids in regulation and health endocrine glands. glands include thyroid, adrenal, hypothalamus, pituitary pineal, ovaries testes play vital functions our body such as growth development, metabolism, mood reproduction controlled by hormones. abnormalities are formed various disorders, some major dis...

Introduction: Alzheimer’s disease (AD) is an age-related neurodegenerative disease, which impairs memory and cognitive function. Walnuts are a dietary source of polyphenols, antioxidants and other compounds with health beneficial effects. These characteristic of walnuts make them perfect candidates for evaluation of their possible effects on neurodegenerative diseases. Therefore the prese...

Brain ischemia induces neuronal loss which is caused in part by excitotoxicity and free radical formation. Here, we report that mangiferin and morin, two antioxidant polyphenols, are neuroprotective in both in vitro and in vivo models of ischemia. Cell death caused by glutamate in neuronal cultures was decreased in the presence of submicromolar concentrations of mangiferin or morin which in tur...

Resveratrol, a polyphenol derived e.g. from red grapes, has been shown to mediate several positive biological actions such as protection of cells against oxidative stress. It can also influence cell signaling, but the mechanisms behind its antioxidant properties are largely unknown. Here we show that RSV reduces oxidative stress and enhances cell survival in PC6.3 cells depending on the concent...

A lot of evidence exists that oxidative stress is the primary cause of neurodegeneration. Neurons are more susceptible to oxidative damage than other cells due to their high oxygen consumption, low activity of antioxidant enzymes, elevated concentration of polyunsaturated fatty acids in the cell membrane, high number of mitochondria, unfavorable space/volume ratio and vicinity of microglia cell...