Diameter, blood flow velocity and volumic flow of the brachial artery were measured in 36 patients with sustained essential hypertension and compared with 25 normal subjects. Both hypertensives and control subjects were classified according to age into those younger than and those older than 40 years. For the determinations, a pulsed Doppler velocimeter with an adjustable range-gated time syste...

Diameter, blood flow velocity and volumic flow of the brachial artery were measured in 36 patients with sustained essential hypertension and compared with 25 normal subjects. Both hypertensives and control subjects were classified according to age into those younger than and those older than 40 years. For the determinations, a pulsed Doppler velocimeter with an adjustable range-gated time syste...

OBJECTIVES Mild hyperhomocysteinaemia, fasting as well as after a methionine load, occurs in families and is associated with premature atherosclerosis. We hypothesised that endothelial dysfunction plays a role in the relation between hyperhomocysteinaemia and clinical vascular disease. METHODS In this study flow-mediated, endothelium-dependent vasodilatation of the brachial artery and, as a m...

Flow-mediated dilation of the brachial or radial artery in response to transient hyperaemic flow, the most widely used test of endothelial function, is only manifest after flow decays back to baseline. We examined whether this dissociation of flow and diameter might be explained by a reduction in transmural pressure generated by high flow. Studies were performed in healthy subjects 20 to 55 yea...

Flow-mediated dilation of the brachial or radial artery in response to transient hyperaemic flow, the most widely used test of endothelial function, is only manifest after flow decays back to baseline. We examined whether this dissociation of flow and diameter might be explained by a reduction in transmural pressure generated by high flow. Studies were performed in healthy subjects 20 to 55 yea...

Materials and methods: Th e study group comprised 33 individuals who underwent TET with suspicion of myocardial ischemia, but no evidence of ischemia and with hypertensive response to TET, and the control group comprised 29 ageand gender-matched subjects. All participants underwent echocardiographic examination, brachial artery ultrasonography, and aortic ultrasonography for the assessment of l...

BACKGROUND Although progressive chronic congestive heart failure (CHF) is associated with elevated systemic vascular resistance and increased impedance to ventricular outflow, the contribution of changes in large artery function has not been well documented in humans. METHODS AND RESULTS We studied 45 patients with a broad range of clinical severity of CHF and compared noninvasive measurement...

The features of the vasoregulating function vascular endothelium have been determined and correlations between haemodynamic metabolic indices established in patients with coronary heart disease associated type II diabetes mellitus. In mellitus comparison without an association significantly higher content blood fibrinogen diameter brachial artery (after decompression) were observed. Direct fast...

PURPOSE Examine the effects of incremental and submaximal exercise on structural and hemodynamic changes in the brachial artery flow parameters using Doppler ultrasonography. MATERIALS AND METHODS Twenty four healthy sedentary males (aged 19.54+/-0.59) performed submaximal (15 minutes heart rate to 75% maximal) and incremental (workload was increased 20W every 3 minutes until exhaustion) exer...

OBJECTIVE Cardiovascular diseases are associated with impaired flow-mediated vasodilation (FMD) and increase in carotid intima-media thickness (IMT). Both FMD and IMT are independent predictors for cardiovascular outcomes. When measuring FMD and nitroglycerine-induced vasodilation in the brachial artery, IMT can also be simultaneously assessed in the same brachial artery. The purpose of this st...