Background: A Boron Neutron Capture Therapy (BNCT) facility, based on a DT neutron generator, with the final goal to find out a potential, alternative, solution to existing BNCT treatment facilities which are based on nuclear reactors is examined. Materials and Methods: With the aim of the MCNP4B Monte Carlo code different beam-shaping assembly (BSA) configurations were considered. Lead was sel...

Abstract The dose analysis of Boron Neutron Capture Therapy (BNCT) on head cancer using the Particle and Heavy Ion Transport Code System (PHITS) has been carried out. purpose this study was determine rate received irradiation time required for therapy BNCT method. research conducted through a simulation approach. PHITS code used to design an epithermal neutron source derived from accelerator de...

BACKGROUND Boron neutron capture therapy (BNCT) is a cell-selective radiation therapy that uses the alpha particles and lithium nuclei produced by the boron neutron capture reaction. BNCT is a relatively safe tool for treating multiple or diffuse malignant tumors with little injury to normal tissue. The success or failure of BNCT depends upon the 10B compound accumulation within tumor cells and...

The paper, in its first part, outlines the place of the fast neutron therapy (FNT) in the concert of radiation therapies by listing the active facilities, comparing technical and statistical data, and summarizing distinct biological properties of fast neutrons. The gross situation of Boron neutron capture therapy (BNCT) is mentioned as well. As well as the number of patients is decreasing, FNT ...

Boron neutron capture therapy (BNCT) is based on the ability of the non-radioactive isotope 10B to capture thermal neutrons and to disintegrate instantaneously. This reaction opens a way to selectively destroy tumour cells after specific uptake of 10B. In this paper, a method based on electron energy-loss spectroscopy is presented for detecting and quantifying boron in freeze-dried cryosections...

We have constructed a formal model on cost-benefit of new technology in health care, and apply it on boron neutron capture therapy (BNCT). We assume that the patient health benefit from getting cured in acute treatment is always higher than the patient utility resulting from any long term treatment or death. This assumption makes it possible to evaluate the monetary cost impacts of a new techno...

background: a boron neutron capture therapy (bnct) facility, based on a dt neutron generator, with the final goal to find out a potential, alternative, solution to existing bnct treatment facilities which are based on nuclear reactors is examined. materials and methods: with the aim of the mcnp4b monte carlo code different beam-shaping assembly (bsa) configurations were considered. lead was sel...

The aim of this study is to compare between proton boron fusion therapy (PBFT) and boron neutron capture therapy (BNCT) and to analyze dose escalation using a Monte Carlo simulation. We simulated a proton beam passing through the water with a boron uptake region (BUR) in MCNPX. To estimate the interaction between neutrons/protons and borons by the alpha particle, the simulation yielded with a v...

Boron Neutron Capture Therapy (BNCT) is a binary radiation treatment modality based on nuclear reactions between thermal neutrons and stable isotope B concentrated primarily in cancer cells. It allows for delivery of high linear energy transfer (LET) radiation ( particles and Li nuclei) to tumors at the cellular level whilst avoiding unnecessary dose deposition to healthy tissue. Until now, mos...