Background Semi-quantitative magnetic resonance imaging (MRI) scoring is more challenging in some anatomic regions than others. Bone marrow lesion (BML) an important feature and may be closely related to clinical outcomes arthritis The Knee Inflammation MRI Scoring System (KIMRISS) scores BML synovitis-effusion from fluid-sensitive sagittal [1] . Via web-based interface, readers place ready-mad...

BACKGROUND Tc-99m methoxy-isobutyl-isonitrile (MIBI) has been reported to be a useful tracer in patients with multiple myeloma (MM). Few articles have reported the potential value of fluorine-18 fluorodeoxyglucose positron emission tomography (FDG-PET) in the evaluation of MM. Therefore, the purpose of this study was to compare the diagnostic abilities of the MIBI scan and the FDG-PET scan in t...

Background—Atherosclerotic lesions are believed to grow via the recruitment of bone marrow–derived monocytes. Among the known murine monocyte subsets, Ly-6C monocytes are inflammatory, accumulate in lesions preferentially, and differentiate. Here, we hypothesized that the bone marrow outsources the production of Ly-6C monocytes during atherosclerosis. Methods and Results—Using murine models of ...

The presence of a low level of M protein in the peripheral blood <3gm/dl which is below the required cut off for the diagnosis of plasma cell myeloma is known as monoclonal gammopathy of undetermined significance (MGUS). Elevated levels of serum M protein and detection of M band on serum protein electrophoresis (SPE) can occur in chronic diseases not related to B cell disorders and not always d...

A 63-year-old man visited the clinic with numbness in the right hand. Magnetic resonance imaging demonstrated multiple low-intensity lesions in the cervical vertebrae and sacrum, which was suspicious of cervical bone metastasis. Fluorodeoxyglucose positron emission tomography/computed tomography revealed areas of increased fluorodeoxyglucose uptake in the thoracic esophagus, sternum and sacrum....

BACKGROUND Atherosclerotic lesions are believed to grow via the recruitment of bone marrow-derived monocytes. Among the known murine monocyte subsets, Ly-6C(high) monocytes are inflammatory, accumulate in lesions preferentially, and differentiate. Here, we hypothesized that the bone marrow outsources the production of Ly-6C(high) monocytes during atherosclerosis. METHODS AND RESULTS Using mur...

BACKGROUND Benign metastatic leiomyoma (BML) is an extremely rare disease. Although uterine leiomyomas are benign histologically, they can metastasize to distant sites. While the incidence is very low, the lung is the organ most frequently affected by BML. Pulmonary BML usually presents as numerous well-defined nodules of various sizes, while the cavitary or cystic features in the nodules are r...

Hairy cell leukemia (HCL) is a rare chronic lymphoproliferative disease. LSV characterized by inflammation of small vessels. Its association in the literature and HCL can be seen etiology, although relationship between 2 diseases far from clear. Here, we aimed to present case with constitutional symptoms, palpable purpuric lesions on body diagnosed as bone marrow biopsy.

Diffusion-weighted MRI (DWI) of the vertebral bone marrow is a clinically important tool for the characterization of bone-marrow pathologies and, in particular, for the differentiation of benign (osteoporotic) and malignant vertebral compression fractures. DWI of the vertebral bone marrow is, however, complicated by some unique MR and tissue properties of vertebral bone marrow. Due to both the ...