نتایج جستجو برای: bone marrow derived mononuclear cells

تعداد نتایج: 1980024  

Journal: :iranian biomedical journal 0
keywan mortezaee parichehr pasbakhsh iraj ragerdi kashani fatemeh sabbaghziarani ameneh omidi adib zendedel

background: bone marrow-derived mesenchymal stem cells (bmmscs) transplantation has been considered as a promising milestone in liver fibrosis treatment. however, low amounts of homing are a major obstacle. we aimed to investigate the role of melatonin pretreatment in bmmsc homing into experimental liver fibrosis. methods: bmmscs were obtained, grown, propagated and preconditioned with 5 µm mel...

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Journal: :European Journal of Vascular and Endovascular Surgery 2019

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Journal: Iranian Journal of Basic Medical Sciences 2018
Ali Badiee, Amin Nikpoor, Hamed Eshaghian, Mahmoud Reza Jaafari, Maryam Shahryari, Razieh Ghoorchian, Sara Shokooh Saremi, Seyed Amir Jalali,

Objective(s): Dendritic cells (DCs) play a critical role in activation of T cell responses. Induction of type1 T helper (Th1) immune response is essential to generate protective immunity against cutaneous leishmaniasis. The intrinsic tendency of liposomes to have interaction with antigen-presenting cells is the main rationale to utilize liposomes as antigen carriers. In the present study, the e...

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Journal: :Bone and mineral 1987
F P van de Wijngaert M C Tas J W van der Meer E H Burger

We studied the growth of mononuclear phagocytes (MPs) and mononuclear osteoclast precursor-resembling (OCP-like) cells from freshly isolated whole mouse bone marrow. Expression of tartrate-resistant acid phosphatase (TRAcP) served as a general marker for the identification of OCP-like cells. Bone resorbing capacity of the cultured cells was studied in a coculture assay with periost-free fetal b...

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ژورنال: مجله دانشگاه علوم پزشکی زنجان 2015
آتشی, امیر, زمانی, هما, پرهیزکار, فاطمه, کاویانی جبلی, سعید,

Background and Objective: Mobilization of Hematopoietic Stem Cells (HSCs) for transplantation and the importance of -adrenergic signals in induction of this process have been well investigated. However, little is known about the role of -adrenergic signals in mobilization of HSCs and factors influenced by these signals. The Chemokine Stromal Derived Factor -1 (SDF-1) which is expressed by hum...

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Journal: :The Journal of Cell Biology 1984
K J Ibbotson G D Roodman L M McManus G R Mundy

The predominant cell responsible for bone resorption, the multinucleated osteoclast, has been difficult to study because of inaccessibility. When feline marrow-derived mononuclear cells are established in long-term culture, multinucleated cells form within 48 h, reaching maximum numbers at 16 d. We have observed that these cultured cells have many of the features of osteoclasts. Morphologically...

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Journal: :Journal of Biological Chemistry 1989

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2014
S. Hogendoorn B. J. Duijnisveld S. G. van Duinen B. C. Stoel J. G. van Dijk W. E. Fibbe R. G. H. H. Nelissen

OBJECTIVES Traumatic brachial plexus injury causes severe functional impairment of the arm. Elbow flexion is often affected. Nerve surgery or tendon transfers provide the only means to obtain improved elbow flexion. Unfortunately, the functionality of the arm often remains insufficient. Stem cell therapy could potentially improve muscle strength and avoid muscle-tendon transfer. This pilot stud...

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Journal: :Journal of Cell Science & Therapy 2014

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2016
Fernanda F. Cruz Zachary D. Borg Meagan Goodwin Amy L. Coffey Darcy E. Wagner Patricia R.M. Rocco Daniel J. Weiss

UNLABELLED Systemic administration of bone marrow-derived mononuclear cells (BMDMCs) or bone marrow-derived mesenchymal stromal cells (MSCs) reduces inflammation and airway hyperresponsiveness (AHR) in a murine model of Th2-mediated eosinophilic allergic airway inflammation. However, since BMDMCs are a heterogeneous population that includes MSCs, it is unclear whether the MSCs alone are respons...

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