OBJECTIVE The present study was aimed at investigating bone involvement secondary to rotator cuff calcific tendonitis at ultrasonography. MATERIALS AND METHODS Retrospective study of a case series. The authors reviewed shoulder ultrasonography reports of 141 patients diagnosed with rotator cuff calcific tendonitis, collected from the computer-based data records of their institution over a fou...

Receptor activator of nuclear factor κB ligand (RANKL) is critically involved in bone erosion of rheumatoid arthritis (RA). We previously reported association between younger age at onset of RA and a RANKL promoter SNP that conferred an elevated promoter activity via binding to a transcription factor SOX5. Here we study the regulation of SOX5 levels in relation to RANKL expression in RA synovia...

PURPOSE To describe the MR and CT imaging features of hemangiopericytoma and to identify the characteristics that might distinguish them from meningioma. METHODS We retrospectively reviewed the CT and MR findings in 34 pathologically proved cases of hemangiopericytoma. We evaluated the size, shape, and location of the tumor; the presence of hydrocephalus, edema, and mass effect; the type of d...

INTRODUCTION Inflammatory destructive arthritis, like rheumatoid arthritis (RA), is characterized by invasion of synovial fibroblasts (SF) into the articular cartilage and erosion of the underlying bone, leading to progressive joint destruction. Because fibroblast activation protein alpha (FAP) has been associated with cell migration and cell invasiveness, we studied the function of FAP in join...

Glenohumeral osteoarthritis is the most common reason for shoulder replacement. Total shoulder arthroplasty provides reliable pain relief and restoration of function, with implant survivorship reported at 85% at 15 years. Glenoid component wear and aseptic loosening are among the most common reasons for revision. Glenoid wear characteristics have been correlated with, among other things, the de...

INTRODUCTION Pathological bone changes differ considerably between inflammatory arthritic diseases and most studies have focused on bone erosion. Collagen-induced arthritis (CIA) is a model for rheumatoid arthritis, which, in addition to bone erosion, demonstrates bone formation at the time of clinical manifestations. The objective of this study was to use this model to characterise the histolo...

Bone dissection is an important component of many surgical procedures. In this paper, we discuss a haptic and visual simulation of a bone cutting burr, that it is being developed as a component of a training system for temporal bone surgery. We use a physically motivated model to describe the burr–bone interaction, that includes haptic forces evaluation, the bone erosion process and the resulti...