as the ADO, DOSE, HADO, CPI, etc., have been developed and validated as potential multidimensional tools to evaluate the risk of mortality in COPD patients [4] . The ADO index (age, dyspnea, and airway obstruction) was first proposed and validated by Puhan et al. [5] in two different COPD cohorts: a Swiss population of severe COPD and a Spanish population of COPD recruited after their first adm...

OBJECTIVE To describe the self-expanding endobronchial occluder, as utilized in bronchoscopic lung volume reduction, with a 36 month follow-up procedure. METHODS Twenty-three subjects with severe emphysema were recruited and underwent flexible bronchoscopic placement of self-expanding endobronchial occluders. Outcomes were assessed at 1 week, 1-month, 3-, 6-, 12-, 24-, and 36-month intervals....

INTRODUCTION Several differences have been reported in the clinical characteristics of chronic obstructive pulmonary disease (COPD) between men and women. Differences have been found in the association between respiratory symptoms and lung function, and in the factors associated with dyspnea. This raises the question of whether there are differences between the sexes in the relationship between...

Few studies show patient outcomes over time in chronic obstructive pulmonary disease (COPD). In the present study, we monitored forced expiratory volume in the first second (FEV₁) and other manifestations of the disease over 3 years in 133 COPD patients (69% males, age = 65 ± 9 years, FEV₁ = 59 ± 25%) evaluated at baseline. During follow-up, 15 patients (11%) died and 23 (17%) dropped out. Meas...

OBJECTIVE To evaluate an entirely outpatient-based program of pulmonary rehabilitation in patients with chronic obstructive pulmonary disease COPD, using St.George's Respiratory questionnaire (SGRQ), the 6-minutes walking test (6-MWT) and BODE index as the primary outcome measures. METHODS A prospective, parallel-group controlled study of an outpatient rehabilitation program in 80 patients wi...

BACKGROUND The progression of obstructive airway diseases (OADs) including asthma, chronic obstructive pulmonary disease (COPD) and asthma-COPD overlap syndrome in older adults is not well understood. OBJECTIVE To examine the prognosis of OADs and to identify potential determinants for longitudinal changes in clinical outcomes. METHODS We consecutively recruited 99 older adults (>55 years) ...

OBJECTIVE The purpose was to assess functional (balance L-L and A-P displacement, sit-to-stand test (SST) and Tinetti scale - balance and gait) and neurophysiological aspects (patellar and Achilles reflex and strength) relating these responses to the BODE Index. INTRODUCTION The neurophysiological alterations found in patients with chronic obstructive pulmonary disease (COPD) are associated w...