We have recently identified by cDNA cloning a set of genes that are rapidly activated in mouse 3T3 cells by serum or purified growth factors. Here we report that the cDNA (clone 268) derived from one of these immediate early genes (zif/268) encodes a protein with three tandem "zinc finger" sequences typical of a class of eukaryotic transcription factors. The mRNA of zif/268 is present in many o...

OBJECTIVE Since January 2008, obese women with type 2 diabetes were advised to gain 0-5 kg during pregnancy. The aim with this study was to evaluate fetal growth and perinatal morbidity in relation to gestational weight gain in these women. RESEARCH DESIGN AND METHODS A retrospective cohort comprised the records of 58 singleton pregnancies in obese women (BMI ≥30 kg/m(2)) with type 2 diabetes...

OBJECTIVE To investigate association between dietary habits and asthma severity in children. DESIGN Cross-sectional study. SETTING Two teaching hospitals in Brazil. PARTICIPANTS Cases (n=268) were children (3-12yr) with persistent asthma and age-matched controls (n=126) were those with intermittent asthma. MAIN OUTCOME MEASURES Dietary habits were determined based on food consumption in...

Background: Endotracheal tube (ETT) intracuff pressure (PINTRACUFF) monitoring is not a mandatory part of daily anesthetic practice in many countries. Correct PINTRACUFF required to ensure adequate ventilation, prevent aspiration, and avoid complications. The aim this study was objectively measure the ETTs among patients from an Australian tertiary hospital define range values seen setting with...

Abstract Climate change can potentially have great impacts on wintertime precipitation and stagnant conditions, which are critical for both water resources particulate matter (PM), in California. This study utilizes the Weather Research Forecasting model to dynamically downscale a bias-corrected coarse-resolution global climate dataset from Coupled Model Intercomparison Project Phase 5 (CMIP5) ...

Bioassay-guided fractionation of an EtOAc/MeOH extract of Adenaria floribunda young leaves using MCF-7, H-460, and SF-268 cancer cell lines yielded four new active compounds named adenaflorins A-D (1-4). Their chemical structures were determined by spectroscopic means. Adenaflorin A (1) was the most cytotoxic.

Background: It is challenging to measure BMI accurately in population studies because it an expensive and time-consuming task. As a result, subjectively measured BMI, calculated from self-reported height weight, which we know be inaccurate, often used. The purpose of this study determine whether using different, subjectiv...

Bromoacetophenone (2-bromo-1-phenylethanone) has been characterized as an affinity reagent for human aldehyde dehydrogenase (EC 1.2.1.3) [MacKerell, MacWright & Pietruszko (1986) Biochemistry 25, 5182-5189], and has been shown to react specifically with the Glu-268 residue [Abriola, Fields, Stein, MacKerell & Pietruszko (1987) Biochemistry 26, 5679-5684] with an apparent inactivation stoichiome...