نتایج جستجو برای: blood coagulation factors
تعداد نتایج: 1686867 فیلتر نتایج به سال:
Upon vascular injury, locally controlled haemostasis prevents life-threatening blood loss and ensures wound healing. Intracellular material derived from damaged cells at these sites will become exposed to blood components and could contribute to blood coagulation and pathological thrombus formation. So far, the functional and mechanistic consequences of this concept are not understood. Here, we...
Burn injury is traditionally referred to as a common triggering cause of acute coagulopathy, ranging from subclinical activation of coagulation to fulminant overt Disseminated Intravascular Coagulation (DIC). Coagulopathy associated with burn injury was well recognized as early as the 1970s.1,2 Coagulopathy in burn patients is considered to be driven by an endothelial injury, release of tissue ...
A survey of the results of recent work indicates that at least six different substances are concerned in one way or another in the process of blood coagulation; namely, fibrinogen, thrombin, prothrombin, calcium, antithrombin and the so-called zymoplastic or thromboplastic substances furnished bv the body cells in general, including the blood corpuscles. With regard to the last mentioned factor...
Hemophilia B is a rare blood coagulation disorder. Complications such as bleeding and hematoma can cause necrosis of flaps, wound disruption, and the disturbance of wound healing. In particular, guidelines for flap operations in hemophilia B patients have still not been defined, and case reports are rare. We reconstructed the heel of a 41-year-old male hemophilia B patient using a reverse sural...
JOSEPH F. Ross, M.D., Editor
OBJECTIVES Bee venom (BV) is a complex mixture of proteins and contains proteins such as phospholipase and melittin, which have an effect on blood clotting and blood clots. The mechanism of action of honey bee venom (HBV, Apis mellifera) on human plasma proteins and its anti-thrombotic effect were studied. The purpose of this study was to investigate the anti-coagulation effect of BV and its ef...
Blood coagulation factors and other proteins, with modulatory effects or modulated by the coagulation cascade have been reported to affect the pathophysiology of the central nervous system (CNS). The protease-activated receptors (PARs) pathway can be considered the central hub of this regulatory network, mainly through thrombin or activated protein C (aPC). These proteins, in fact, showed pecul...
Study of the platelets from the viewpoint of the blood coagulation mechanisms seems likely to be helpful for increasing our knowledge of thrombosis, and bleeding tendencies in thrombasthenias and thrombopathias. A logical approach to their study is the differentiation of their properties and where possible to ascribe those properties to individual components. Platelet factors 1, 3 and 4 are con...
BACKGROUND AND THE PURPOSE OF THE STUDY The quality of some of the human plasma derived drugs such as coagulation factor VIII and coagulation factor IX which can be used for the treatment of hemophilia A and B, depends on their activity which may be affected by filtration. In this study the quality of plasma with respect to coagulation factors FVII, FVIII, FIX, FV, FXI, Fibrinogen, antithrombin...
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