We have conducted a preliminary analysis of kiloton class, anomalous, mining blasts in Wyoming using IMS seismic data. This research has begun on two fronts. We are examining well documented mine blasts in the Powder River Basin trend in Wyoming using the Pinedale seismic array (PDAR) and the single station ULM. These data are being used with near-regional video, seismic and acoustic data colle...

background: this cross sectional comparative study was performed to compare the mean fluorescence intensity of cluster of differentiation 45 between healthy individuals and patients with acute lymphoblastic leukemia. patients and methods: thirty three healthy individuals (mean age 11 years) and 41 patients with b cell acute lymphoblastic leukemia (mean age 7 years) were enrolled in the study in...

Dear Editor, We would like to thank Bennett JM and Wells DA for their insightful comments [1] regarding our manuscript “Lee et al. An unusual case of myeloperoxidase-positive acute megakaryoblastic leukemia. Ann Lab Med 2015;35:466-8” [2]. The case that we reported was diagnostically challenging, and our conclusions were based on various lines of evidence. In particular, the morphological featu...

Leukemic blasts from patients with acute nonlymphoid leukemia were examined for the presence of Ig, receptors for IgGFc, and for their capacity to mediate antibody-dependent cellular cytotoxicity (ADCC) against chicken red blood cells (RBC) coated with IgG and spontaneous cell-mediated cytotoxicity (SCMC) against cells of K562 cell line. Leukemic blasts from acute myeloblastic leukemia (AML) pa...

In 26 myeloid and lymphoid acute leukemia patients at presentation the capacity to generate interleukin-2 (IL-2)-induced lymphokine-activated killer (LAK) cells effective against the natural killer (NK)-resistant Raji cell line, as well as the susceptibility of the blasts to normal peripheral blood (PB) LAK cells and to autologous LAK effectors was analyzed. The overall PB LAK activity against ...

Stem cell factor (SCF) acts in concert with lineage-specific growth factors to stimulate the growth of hematopoietic colonies. To determine if neoplastic human hematopoietic cells would also respond to SCF, we cultured marrow mononuclear cells from 20 patients with newly diagnosed acute myelogenous leukemia (AML) and two normal donors with SCF, interleukin 3 (IL-3), granulocyte-macrophage colon...

Blasts showing hemophagocytosis have been very rarely reported in acute lymphoblastic leukemia. We report a pediatric case of B lymphoblastic leukemia (BLL) with t(12;21)(p13;q22); TEL-AML1 (ETV6-RUNX1) showing erythrophagocytosis and thrombophagocytosis by leukemic blasts. About 4% of the leukemic blasts in marrow aspirate smears showed phagocytosis of erythrocytes, platelets, or nuclear remna...