Haenggi and colleagues report considerable intra- and inter-individual variability in derived electroencephalogram (EEG) parameters (Bispectral Index (BIS), response entropy and state entropy) recorded in volunteers sedated with midazolam or dexmedetomidine infusions titrated to modified Ramsay scores of 2, 3 and 4, and a remifentanil infusion at a fixed target concentration. Possible explanati...

Miller-Dieker syndrome (MDS) is a rare disorder characterized by type I lissencephaly and a distinctive facial appearance that may include prominent forehead, bitemporal hollowing, and micrognathia. MDS is associated with epilepsy. We here report an 18-month-old girl with MDS who required general anesthesia. The child had an extremely low Bispectral Index (BIS) value prior to undergoing general...

BACKGROUND The bispectral (BIS) index is a processed electroencephalogram (EEG) parameter with extensive validation and demonstrated clinical utility. The study aimed to investigate the correlation between the BIS index and the prognosis of patients with coma in the ICU. METHODS A total of 208 patients with coma in the ICU were enrolled in this study. According to the BIS value, the patients ...

THE Bispectral Index (BIS) monitor (BIS® monitor; Aspect Medical System, Inc., Newton, MA) integrates electroencephalographic data via a proprietary algorithm based on empirical data into a nominal 100 to 0 scale, in which 100 represents the awake state and 0 represents the isoelectric electroencephalogram. The BIS® monitor is highly capable of correctly predicting both the loss and recovery of...

The use of bispectral index (BIS) for monitoring neuronal function under general anesthesia has been expanding in practice. However, the meanings of the values are not always clear and have been shown to be altered by such drugs as ketamine, ephedrine, and physostigmine. Presented here is a case of increasing BIS in response to noradrenergic beta receptor stimulation via the administration of i...

patients warranted additional i.v. anaesthetic prior to application of the electrical stimulus. Fortunately, neither of the patients reported awareness of the procedural events. Consequently, we no longer use bispectral index monitoring alone to assess pre-ictal anaesthetic depth in patients receiving ECT. Moreover, Zand and colleagues recently reported that the BISwas not a reliable monitorof ...

background : hyperbaric and isobaric bupivacaine has been shown to reduce bispectral index (bis) during spinal anesthesia. the aim of this study was to compare the effect of isobaric bupivacaine and hyperbaric bupivacaine on the bis during cesarean section with spinal anesthesia. methods : in this double-blind randomized controlled clinical trial, 84 pregnant women with asa ( american society o...

Abbreviations TIVA, Total intravenous anesthesia; TCI, target-controlled infusion; BIS, Bispectral Index; EDM, Esophageal ultrasonography monitoring; TBRI, Theodor Bilharz Research Institute; ASA, American society of anesthesiologists; MBP, mean blood p HR, heart rate; BMI, body mass index; Ce, effect site concentration; TOF, train of four; Ftc, flow time corrected; PV, peak velocity; SD distan...