A lesson utilizing a coarse-grained (CG) Gō-like model has been implemented into the CHARMM INterface and Graphics (CHARMMing) web portal (www.charmming.org) to the Chemistry at HARvard Macromolecular Mechanics (CHARMM) molecular simulation package. While widely used to model various biophysical processes, such as protein folding and aggregation, CG models can also serve as an educational tool ...

Objective: Evaluating the effect of antenatal betamethasone on the biophysical profile and Doppler indices of umbilical and middle cerebral arteries. Materials and Methods: Twenty-five preterm labor singleton pregnancies (gestational age, 26-34 weeks) were studied prospectively. These patients received two consecutive doses of betamethasone 24 hours apart to accelerate pulmonary maturation. Fet...

the diagnostic value of three fetal movements counting in one hour by mother in the diagnosis of decreased fetal movements kamalifard m[1], ghojazadeh m[2], abbasalizadeh sh[3], ghatrehsamani f[4], rabiei l[5]* received: 1 jun, 2012 accepted: 25 aug, 2012abstractbackground & aims: fetal movement counting is a method that used by the mother to quantify her baby's movements. since 1970s a va...

Single-molecule spectroscopy (SMS) is a powerful experimental technique used to investigate a wide range of physical, chemical, and biophysical phenomena. The merit of SMS is that it does not require ensemble averaging, which is found in standard spectroscopic techniques. Thus SMS yields insight into complex fluctuation phenomena that cannot be observed using standard ensemble techniques. We in...

Current approaches to conservation and natural-resource management often focus on single objectives, resulting in many unintended consequences. These outcomes often affect society through unaccounted-for ecosystem services. A major challenge in moving to a more ecosystem-based approach to management that would avoid such societal damages is the creation of practical tools that bring a scientifi...

The line of scholarship dominating Anglophone geographers’ approaches to studying economic geography since 1980 can be characterized as geographical political economy; an approach prioritizing commodity production over market exchange. Here the spatialities of capitalism co-evolve with its economic processes and economic, political, cultural and biophysical processes are co-implicated with one ...

Single molecule detection methods, such as nanopore sensors have found increasing importance in applications ranging from gaining a better understanding of biophysical processes to technology driven solutions such as DNA sequencing. However, challenges remain especially in relation to improving selectivity to probe specific targets or to alternatively enable detection of smaller molecules such ...

Actomyosin contraction and relaxation in a monolayer is a fundamental biophysical process in development and homeostasis. Current methods used to characterize the mechanodynamics of monolayers often involve cells grown on solid supports such as glass or gels. The results of these studies are fundamentally influenced by these supporting structures. Here we describe a new method for measuring the...

The mean square displacement is a central tool in the analysis of single-particle tracking experiments, shedding light on various biophysical phenomena. Frequently, parameters are extracted by performing time averages on single-particle trajectories followed by ensemble averaging. This procedure, however, suffers from two systematic errors when applied to particles that perform anomalous diffus...

BACKGROUND The study aimed to evaluate the combined effect of Pulsed Electromagnetic Field (PEMF) biophysical stimulation and bone marrow concentrate (BMC) in osteochondral defect healing in comparison to the treatment with scaffold alone. METHODS An osteochondral lesion of both knees was performed in ten rabbits. One was treated with a collagen scaffold alone and the other with scaffold seed...