Background Recent advances in blood-based biomarkers have shown promising abilities to estimate brain pathological statuses related amyloid-β (Aβ) deposition, phosphorylated tau and neurodegeneration using minimally invasive methods. The objective of this study was evaluate the potential ATN classification, by analyzing relevance plasma imaging biomarkers. Method There were 161 subjects, consis...

the chick model is a useful research tool to investigate the development of the enteric nervous system (ens). recognition of appropriate markers for detection of chick enteric ganglia will allow better utilization of this model to study abnormalities of the ens. this study aimed to validate a set of antibodies for avian ens studies on wax sections. the specimens were taken from jejunum and colo...

polybrominated diphenyl ethers (pbdes) have been widely used in many products as flameretardants, which resulted in their release into the environment. little is known about the impact of coexisting pbdes on organisms. in this study, the in vivo effects of bde-47 and bde-99 on a suite of biomarkers, acetyl cholinesterase (ache), ethoxyresorufin-o-deethylase (erod), glutathione-s-transferase (gs...

background: high sensitive c-reactive protein (hs-crp) is a systemic inflammatory marker that is produced in a large amount by hepatocytes in response to interleukin-1 (il-1), il-6 and tumor necrosis factor after ischemic stroke. methods: measurement of hs-crp in the first 24 hours of onset in 162 patients suffering from ischemic stroke was done. relation of crp with the risk of early mortality...

introduction: amajor problem in the treatment of cancer is the lack of an appropriate method for the early diagnosis of the disease. the chemical reaction within an organ may be reflected in the form of proteomic patterns in the serum, sputum, or urine. laser mass spectrometry is a valuable tool for extracting the proteomic patterns from biological samples. a major challenge in extracting such ...

background: silicosis is considered an oxidative stress related disease that can lead to the development of lung cancer. in this study, our purpose was to analysis of volatile organic compounds (vocs) in the exhaled breath of workers exposed to silica containing dust and compare peak area of these compounds with silicosis patients and healthy volunteers (smokers and nonsmokers) groups. methods ...

conclusions twelve weeks of two grams of ginger supplementation showed beneficial effects on some nafld characteristics. further studies are recommended to assess the long-term supplementation effects. results ginger supplementation resulted in a significant reduction in alanine aminotransferase, γ-glutamyl transferase, inflammatory cytokines, as well as the insulin resistance index and hepatic...

conclusions both add-on ldt and switching to peg-ifn-α2a were satisfactory and optimal treatments for chb patients with poor responses to adv. both rescue strategies resulted in significant reductions in serum viral load and alt levels, and were associated with high rate of serological outcomes in our hospital. patients and methods ninety-seven chb patients with hbv dna > 2 log10 copies/ml 48 w...

introduction: we evaluated the incidence and clinical outcome of patients with hypertensive acute ischemic stroke (ais) admitted to a tertiary care center in central india. in addition, we examined the status of stroke biomarkers namely neuron-specific enolase (nse), glial specific protein (s-100ββ), and inter-α-trypsin inhibitor heavy chain 4(itih4) in the serum of patients suffering from ais ...