نتایج جستجو برای: biologics
تعداد نتایج: 4474 فیلتر نتایج به سال:
BACKGROUND The prognosis of children with juvenile dermatomyositis (JDM) has improved remarkably since the 1960's with the use of corticosteroid and immunosuppressive therapy. Yet there remain a minority of children who have refractory disease. Since 2003 the sporadic use of biologics (genetically-engineered proteins that usually are derived from human genes) for inflammatory myositis has been ...
PURPOSE Training intensities are frequently prescribed as relative workloads based on a single reference value (e.g. maximum oxygen uptake). However, exercise-induced physical strain is multifaceted and large interindividual variability in intensity markers has been reported for constant load exercise with standardized relative intensity. This questions the accuracy of (univariate) relative int...
OBJECTIVE To investigate the risk of squamous cell and basal cell skin cancer in patients with rheumatoid arthritis naive to biologic drugs, in patients starting tumour necrosis factor (TNF) inhibitor treatment, and in the general population. DESIGN Population based cohort study. SETTING Nationwide data from Sweden. PARTICIPANTS Cohort of patients with rheumatoid arthritis naive to biolog...
1 The Biodesign Institute, Arizona State University, 1001 S. McAllister Avenue, Tempe, AZ 85287, USA 2 School of Life Sciences, Arizona State University, 1001 S. McAllister Avenue, Tempe, AZ 85287, USA 3Department of Science and Technology for Agriculture, Forestry, Nature and Energy (DAFNE), University of Tuscia, Via San Camillo de Lellis snc, 01100 Viterbo, Italy 4Department of Biological Sys...
BACKGROUND & AIMS Use of immunosuppressants and inflammatory bowel disease (IBD) may increase the risk of pneumonia caused by Pneumocystis jirovecii (PJP). We assessed the risk of PJP in a population-based cohort of patients with IBD treated with corticosteroids, immune-suppressive medications, and biologics. METHODS We performed a population-based cohort study of residents of Olmsted County,...
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