نتایج جستجو برای: bioliquid filled microtubules

تعداد نتایج: 67085  

Journal: :eLife 2021

Microtubules that assemble the mitotic spindle are generated by centrosomal nucleation, chromatin-mediated and nucleation from surface of other microtubules mediated augmin complex. Impairment in apical progenitors developing mouse brain induces p53-dependent apoptosis causes non-lethal microcephaly. Whether disruption non-centrosomal has similar effects is unclear. Here, we show, using embryos...

Journal: :PNAS nexus 2023

Abstract The cytoskeleton is a major focus of physical studies to understand organization inside cells given its primary role in cell motility, division, and mechanics. Recently, protein condensation has been shown be another intracellular organizational strategy. Here, we report that the microtubule crosslinking proteins, MAP65-1 PRC1, can form phase separated condensates at physiological salt...

Journal: :The Journal of Cell Biology 1974
J. R. McIntosh

Bridges between microtubules have been studied with the electron microscope in the axostyle of Saccinobaculus and in various tubule systems of chicken testis, including the helix of tubules surrounding the elongating spermatid nucleus and the flagellum of the sperm tail. In addition to the previously described periodic bridges, evidence is presented that nonperiodic bridges exist between certai...

Journal: :The Plant cell 2009
Kathleen L Farquharson

Epidermal hypocotyl cells are characterized by a highly structured cortical microtubule array, consisting of bundles of polarized, parallel microtubules that gradually migrate across the cortex in a rotary fashion (Chan et al., 2007). In animal cells, microtubules arise from centrosomes; however, plant cells lack centrosomes, and microtubules are thought to self-organize into structured arrays ...

M Mosavi Mashhadi M Motamedi,

This work is conducted to obtain mechanical properties of microtubule. For this aim, interaction energy in alpha-beta, beta-alpha, alpha-alpha, and beta-beta dimers was calculated using the molecular dynamic simulation. Force-distance diagrams for these dimers were obtained using the relation between potential energy and force. Afterwards, instead of each tubulin, one sphere with 55 KDa weight ...

Journal: :Parasitology 2006
D Bahia L G A Avelar F Vigorosi D Cioli G C Oliveira R A Mortara

Schistosoma mansoni eggs, miracidia and primary sporocysts were labelled with phalloidin-rhodamine to visualize filamentous actin structures. Analysis of these forms by confocal fluorescence microscopy revealed the presence of previously well-defined circular and longitudinal muscle layers. Besides these muscular layers that sustain and provide motility to these parasite forms, we found in thes...

Journal: :Cell reports 2016
Amber L Jolly Chi-Hao Luan Brendon E Dusel Sara F Dunne Michael Winding Vishrut J Dixit Chloe Robins Jennifer L Saluk David J Logan Anne E Carpenter Manu Sharma Deborah Dean Andrew R Cohen Vladimir I Gelfand

Long-distance intracellular transport of organelles, mRNA, and proteins ("cargo") occurs along the microtubule cytoskeleton by the action of kinesin and dynein motor proteins, but the vast network of factors involved in regulating intracellular cargo transport are still unknown. We capitalize on the Drosophila melanogaster S2 model cell system to monitor lysosome transport along microtubule bun...

Journal: :Developmental Cell 2004

Journal: :Journal of Clinical Investigation 1980

Journal: :Journal of Cell Biology 2006

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