Certain bioflavonoids inhibit the glycolysis of variety of tumor cells by interfering with the generation of adenosine diphosphate and inorganic phosphate which are required for glycolysis. Tetra- and pentahydroxy flavones with hydroxyl groups as 3, 3', 4', 5, and 7 (e.g., quercetin) are the most active. They inhibit the activity of isolated Na+-K+-adenosinetriphosphatase of the plasma membrane...

According to Ayurveda there are large numbers of traditional medicinal uses of Ziziphus species and the reasons behind the medicinal potential of this plant are because of some allied substances such as ascorbic acid, thiamine, riboflavin and bioflavonoids and pectin-A. Therefore, this plant is a valuable source of phytochemicals, bioactives, vitamins etc. which makes it to be effective in curi...

The basic parapharmaceuticals in the Polish diet include natural anti-oxidants bioflavonoids found in berry fruit. They were proven to have the ability to regulate genetic transcription and increase the synthesis of nitric oxide which counteracts dysfunction of the vascular endothelium. They also display anti-oxidant action through the inhibiting effect on cyclooxygenase COX-2, and increase the...

Oxidative stress is one of the important causes of the type 1 diabetes induced changes in the sperm quality. Bioflavonoids, Rutin 10 mg/Kg and Naringin 10 mg/Kg were evaluated for their protective effects on sperm parameters, oxidative stress, and histopathology of type 1 diabetic rats. Results demonstrated the reduction in sperm count, sperm motility and vitality in diabetic rats. Mass drug ad...

Anthocyanins, which are natural plant pigments from the flavonoid family, represent substantial constituents of the human diet. Because some other bioflavonoids are known to have estrogenic activity, the aim of this study was to determine the estrogenic activity of the anthocyanine aglycones. Binding affinity to the estrogen receptor-alpha was 10,000- to 20,000-fold lower than that of the endog...

Abstract The researchers demonstrate the development of a novel Prodosome technology-derived PL425 PEC phytonutrient-enriched electrolyte formulation and its significant contribution in fluid homeostasis as well enhanced neuromuscular function, cardio-protection, pulmonary, other physiological cellular organ functions. Electrolytes enriched phytonutrients including polyphenolic bioflavonoids, a...