Cellular processes are governed and coordinated by a multitude of biopathways. A pathway can be viewed as a complex network of biochemical reactions. The dynamics of this network largely determines the functioning of the pathway. Hence the modeling and analysis of biochemical networks dynamics is an important problem and is an active area of research. Here we review quantitative models of bioch...

Mathematical simulation of biological processes is a big challenge in both of biology and computer science. This enables biologists to approach the mechanism of life as systems, however, it’s an extremely computation intensive tasks. We’ve developed an FPGA-based hardware accelerator for biochemical simulations. This accelerator has a dedicated pipeline to solve ODEs by its dedicated pipeline m...

We studied blood samples from 529 Spanish ibexes (Capra pyrenaica) from different Andalusian mountain ranges in southern Spain, primarily from Sierra Nevada. For each sample, 13 hematologic and 32 biochemical parameters were analyzed. Within this database, we selected values obtained from live, free-ranging, physically restrained, clinically normal animals to determine reference intervals for t...

G6PD is rate limiting enzyme in pentose phosphate pathway (PPP), have effective physiological role supply of NADPH by converting it into Glucose-6-phosphate to phospogluconate which acts as a major cell reductant and useful survival. Brain highly sophisticated organ our body requires continuous energy form glucose. Daily requirement brain glucose 120gm. plays key it. According WHO 75% world pop...

MOTIVATION Clustering of chemical and biochemical data based on observed features is a central cognitive step in the analysis of chemical substances, in particular in combinatorial chemistry, or of complex biochemical reaction networks. Often, for reasons unknown to the researcher, this step produces disappointing results. Once the sources of the problem are known, improved clustering methods m...